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Deficiency of the lipid flippase ATP10A causes diet-induced dyslipidemia in female mice

Genetic association studies have linked ATP10A and closely related type IV P-type ATPases (P4-ATPases) to insulin resistance and vascular complications, such as atherosclerosis. ATP10A translocates phosphatidylcholine and glucosylceramide across cell membranes, and these lipids or their metabolites...

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Detalles Bibliográficos
Autores principales: Norris, Adriana C., Yazlovitskaya, Eugenia M., Zhu, Lin, Rose, Bailey S., May, Jody C., Gibson-Corley, Katherine N., McLean, John A., Stafford, John M., Graham, Todd R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10312798/
https://www.ncbi.nlm.nih.gov/pubmed/37398141
http://dx.doi.org/10.1101/2023.06.16.545392

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