Combinatorial chloride and calcium channelopathy in myotonic dystrophy

Myotonic dystrophy type 1 (DM1) involves misregulated alternative splicing for specific genes. We used exon or nucleotide deletion to mimic altered splicing of genes central to muscle excitation-contraction coupling processes in mice. Mice with forced-skipping of exon 29 in Ca(V)1.1 calcium channel...

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Detalles Bibliográficos
Autores principales: Cisco, Lily A., Sipple, Matthew T., Edwards, Katherine M., Thornton, Charles A., Lueck, John D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10312834/
https://www.ncbi.nlm.nih.gov/pubmed/37398406
http://dx.doi.org/10.1101/2023.05.29.542752

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