Mycobacterium tuberculosis resides in lysosome-poor monocyte-derived lung cells during chronic infection

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Mycobacterium tuberculosis (Mtb) persists in lung myeloid cells during chronic infection. However, the mechanisms allowing Mtb to evade elimination are not fully understood. Here, we determined that in chronic phase, CD11c(lo) monocyte-derived lung cells termed MNC1 (mononuclear cell subset 1), harb...

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Detalles Bibliográficos
Autores principales: Zheng, Weihao, Chang, I-Chang, Limberis, Jason, Budzik, Jonathan, Zha, Beth Shoshana, Howard, Zachary, Chen, Lucas, Ernst, Joel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Journal Experts 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10312915/
https://www.ncbi.nlm.nih.gov/pubmed/37398178
http://dx.doi.org/10.21203/rs.3.rs-3049913/v1
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