Peripheral MC1R activation modulates immune responses and is neuroprotective in a mouse model of Parkinson’s disease

BACKGROUND: Melanocortin 1 receptor (MC1R) is a key pigmentation gene, and loss-of-function of MC1R variants that produce red hair may be associated with Parkinson’s disease (PD). We previously reported compromised dopaminergic neuron survival in Mc1r mutant mice and dopaminergic neuroprotective eff...

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Detalles Bibliográficos
Autores principales: Srivastava, Pranay, Nishiyama, Shuhei, Lin, Sonia H, Srivastava, Akriti, Su, Chienwen, Peng, Weiyi, Levy, Michael, Schwarzschild, Michael, Xu, Yuehang, Chen, Xiqun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Journal Experts 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10312952/
https://www.ncbi.nlm.nih.gov/pubmed/37398302
http://dx.doi.org/10.21203/rs.3.rs-3042571/v1

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