Intracellular Calcium links Milk Stasis to Lysosome Dependent Cell Death by Activating a TGFβ3/TFEB/STAT3 Pathway Early during Mammary Gland Involution

Involution of the mammary gland after lactation is a dramatic example of coordinated cell death. Weaning causes distension of the alveolar structures due to the accumulation of milk, which, in turn, activates STAT3 and initiates a caspase-independent but lysosome-dependent cell death (LDCD) pathway....

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Detalles Bibliográficos
Autores principales: Jeong, Jaekwang, Lee, Jongwon, Talaia, Gabriel, Kim, Wonnam, Song, Junho, Hong, Juhyeon, Yoo, Kwangmin, Gonzalez, David, Athonvarangkul, Diana, Shin, Jaehun, Dann, Pamela, Haberman, Ann, Kim, Lark Kyun, Ferguson, Shawn, Choi, Jungmin, Wysolmerski, John
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Journal Experts 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10312953/
https://www.ncbi.nlm.nih.gov/pubmed/37398309
http://dx.doi.org/10.21203/rs.3.rs-3030763/v1

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