IgM N-glycosylation correlates with COVID-19 severity and rate of complement deposition

The glycosylation of IgG plays a critical role during human SARS-CoV-2, activating immune cells and inducing cytokine production. However, the role of IgM N-glycosylation has not been studied during acute viral infection in humans. In vitro evidence suggests that the glycosylation of IgM inhibits T...

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Detalles Bibliográficos
Autores principales: Haslund-Gourley, Benjamin, Woloszcuk, Kyra, Hou, Jintong, Connors, Jennifer, Cusimano, Gina, Bell, Mathew, Taramangalam, Bhavani, Fourati, Slim, Mege, Nathan, Bernui, Mariana, Altman, Matthew, Krammer, Florian, van Bakel, Harm, Maecker, Holden, Wigdahl, Brian, Cairns, Charles, Haddad, Elias, Comunale, Mary
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Journal Experts 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10312960/
https://www.ncbi.nlm.nih.gov/pubmed/37398192
http://dx.doi.org/10.21203/rs.3.rs-2939468/v1

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