Cargando…

Autism trends in a medium size coastal town of England

Autism spectrum disorder (ASD) is a complex set of neurodevelopmental conditions which affects just under 1% of the global population. This study aims to investigate the trends in ASD diagnoses in a typical English deprived coastal community over the last two decades. ASD information for patients re...

Descripción completa

Detalles Bibliográficos
Autores principales: Fleet, Benjamin G., Elliott, Alicia, Orwin, Margaret, Spencer, Mark, Sedda, Luigi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10313016/
https://www.ncbi.nlm.nih.gov/pubmed/37390060
http://dx.doi.org/10.1371/journal.pone.0287808
_version_ 1785067032095490048
author Fleet, Benjamin G.
Elliott, Alicia
Orwin, Margaret
Spencer, Mark
Sedda, Luigi
author_facet Fleet, Benjamin G.
Elliott, Alicia
Orwin, Margaret
Spencer, Mark
Sedda, Luigi
author_sort Fleet, Benjamin G.
collection PubMed
description Autism spectrum disorder (ASD) is a complex set of neurodevelopmental conditions which affects just under 1% of the global population. This study aims to investigate the trends in ASD diagnoses in a typical English deprived coastal community over the last two decades. ASD information for patients registered at Fleetwood GP practices were provided for the period between July 1952 to March 2022. The incidence and prevalence were calculated and Poisson regression modelling was employed to estimate the effects of age and sex on the number of ASD diagnoses over time. The study shows that there has been an upward trend in the number of ASD diagnoses over the past two decades. Model’s results showed that sex differences in ASD diagnoses are less pronounced when accounting for time trends. The study findings show that Fleetwood has experienced a similar rise in ASD cases as the rest of the UK, most likely due to increased awareness that may explain the time effects over gender differences. However, due to the small sample size of the study, confirmation of the gender results and identification of the factors determining the temporal trends are needed in order to determine the gender effects in ASD diagnosis.
format Online
Article
Text
id pubmed-10313016
institution National Center for Biotechnology Information
language English
publishDate 2023
publisher Public Library of Science
record_format MEDLINE/PubMed
spelling pubmed-103130162023-07-01 Autism trends in a medium size coastal town of England Fleet, Benjamin G. Elliott, Alicia Orwin, Margaret Spencer, Mark Sedda, Luigi PLoS One Research Article Autism spectrum disorder (ASD) is a complex set of neurodevelopmental conditions which affects just under 1% of the global population. This study aims to investigate the trends in ASD diagnoses in a typical English deprived coastal community over the last two decades. ASD information for patients registered at Fleetwood GP practices were provided for the period between July 1952 to March 2022. The incidence and prevalence were calculated and Poisson regression modelling was employed to estimate the effects of age and sex on the number of ASD diagnoses over time. The study shows that there has been an upward trend in the number of ASD diagnoses over the past two decades. Model’s results showed that sex differences in ASD diagnoses are less pronounced when accounting for time trends. The study findings show that Fleetwood has experienced a similar rise in ASD cases as the rest of the UK, most likely due to increased awareness that may explain the time effects over gender differences. However, due to the small sample size of the study, confirmation of the gender results and identification of the factors determining the temporal trends are needed in order to determine the gender effects in ASD diagnosis. Public Library of Science 2023-06-30 /pmc/articles/PMC10313016/ /pubmed/37390060 http://dx.doi.org/10.1371/journal.pone.0287808 Text en © 2023 Fleet et al https://creativecommons.org/licenses/by/4.0/This is an open access article distributed under the terms of the Creative Commons Attribution License (https://creativecommons.org/licenses/by/4.0/) , which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
spellingShingle Research Article
Fleet, Benjamin G.
Elliott, Alicia
Orwin, Margaret
Spencer, Mark
Sedda, Luigi
Autism trends in a medium size coastal town of England
title Autism trends in a medium size coastal town of England
title_full Autism trends in a medium size coastal town of England
title_fullStr Autism trends in a medium size coastal town of England
title_full_unstemmed Autism trends in a medium size coastal town of England
title_short Autism trends in a medium size coastal town of England
title_sort autism trends in a medium size coastal town of england
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10313016/
https://www.ncbi.nlm.nih.gov/pubmed/37390060
http://dx.doi.org/10.1371/journal.pone.0287808
work_keys_str_mv AT fleetbenjaming autismtrendsinamediumsizecoastaltownofengland
AT elliottalicia autismtrendsinamediumsizecoastaltownofengland
AT orwinmargaret autismtrendsinamediumsizecoastaltownofengland
AT spencermark autismtrendsinamediumsizecoastaltownofengland
AT seddaluigi autismtrendsinamediumsizecoastaltownofengland