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During heat stress in Myxococcus xanthus, the CdbS PilZ domain protein, in concert with two PilZ-DnaK chaperones, perturbs chromosome organization and accelerates cell death

C-di-GMP is a bacterial second messenger that regulates diverse processes in response to environmental or cellular cues. The nucleoid-associated protein (NAP) CdbA in Myxococcus xanthus binds c-di-GMP and DNA in a mutually exclusive manner in vitro. CdbA is essential for viability, and CdbA depletio...

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Detalles Bibliográficos
Autores principales: Seidel, Michael, Skotnicka, Dorota, Glatter, Timo, Søgaard-Andersen, Lotte
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10313047/
https://www.ncbi.nlm.nih.gov/pubmed/37339150
http://dx.doi.org/10.1371/journal.pgen.1010819