Mitochondria-associated regulation in adipose tissues and potential reagents for obesity intervention

INTRODUCTION: A systematic review analysis was used to assess the profile of mitochondrial involvement in adipose tissue regulation and potential reagents to intervene in obesity through the mitochondrial pathway. METHODS: Three databases, PubMed, Web of Science, and Embase, were searched online for...

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Autores principales: Zheng, Yali, Yang, Ni, Pang, Yueshan, Gong, Yanju, Yang, Hong, Ding, Weijun, Yang, Hongya
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Endocrinology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10313115/
https://www.ncbi.nlm.nih.gov/pubmed/37396170
http://dx.doi.org/10.3389/fendo.2023.1132342
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author Zheng, Yali
Yang, Ni
Pang, Yueshan
Gong, Yanju
Yang, Hong
Ding, Weijun
Yang, Hongya
author_facet Zheng, Yali
Yang, Ni
Pang, Yueshan
Gong, Yanju
Yang, Hong
Ding, Weijun
Yang, Hongya
author_sort Zheng, Yali
collection PubMed
description INTRODUCTION: A systematic review analysis was used to assess the profile of mitochondrial involvement in adipose tissue regulation and potential reagents to intervene in obesity through the mitochondrial pathway. METHODS: Three databases, PubMed, Web of Science, and Embase, were searched online for literature associated with mitochondria, obesity, white adipose tissue, and brown adipose tissue published from the time of their creation until June 22, 2022, and each paper was screened. RESULTS: 568 papers were identified, of which 134 papers met the initial selection criteria, 76 were selected after full-text review, and 6 were identified after additional searches. A full-text review of the included 82 papers was performed. CONCLUSION: Mitochondria play a key role in adipose tissue metabolism and energy homeostasis, including as potential therapeutic agents for obesity.
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spelling pubmed-103131152023-07-01 Mitochondria-associated regulation in adipose tissues and potential reagents for obesity intervention Zheng, Yali Yang, Ni Pang, Yueshan Gong, Yanju Yang, Hong Ding, Weijun Yang, Hongya Front Endocrinol (Lausanne) Endocrinology INTRODUCTION: A systematic review analysis was used to assess the profile of mitochondrial involvement in adipose tissue regulation and potential reagents to intervene in obesity through the mitochondrial pathway. METHODS: Three databases, PubMed, Web of Science, and Embase, were searched online for literature associated with mitochondria, obesity, white adipose tissue, and brown adipose tissue published from the time of their creation until June 22, 2022, and each paper was screened. RESULTS: 568 papers were identified, of which 134 papers met the initial selection criteria, 76 were selected after full-text review, and 6 were identified after additional searches. A full-text review of the included 82 papers was performed. CONCLUSION: Mitochondria play a key role in adipose tissue metabolism and energy homeostasis, including as potential therapeutic agents for obesity. Frontiers Media S.A. 2023-06-16 /pmc/articles/PMC10313115/ /pubmed/37396170 http://dx.doi.org/10.3389/fendo.2023.1132342 Text en Copyright © 2023 Zheng, Yang, Pang, Gong, Yang, Ding and Yang https://creativecommons.org/licenses/by/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
spellingShingle Endocrinology
Zheng, Yali
Yang, Ni
Pang, Yueshan
Gong, Yanju
Yang, Hong
Ding, Weijun
Yang, Hongya
Mitochondria-associated regulation in adipose tissues and potential reagents for obesity intervention
title Mitochondria-associated regulation in adipose tissues and potential reagents for obesity intervention
title_full Mitochondria-associated regulation in adipose tissues and potential reagents for obesity intervention
title_fullStr Mitochondria-associated regulation in adipose tissues and potential reagents for obesity intervention
title_full_unstemmed Mitochondria-associated regulation in adipose tissues and potential reagents for obesity intervention
title_short Mitochondria-associated regulation in adipose tissues and potential reagents for obesity intervention
title_sort mitochondria-associated regulation in adipose tissues and potential reagents for obesity intervention
topic Endocrinology
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10313115/
https://www.ncbi.nlm.nih.gov/pubmed/37396170
http://dx.doi.org/10.3389/fendo.2023.1132342
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