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Senolytic treatment with dasatinib and quercetin does not improve overall influenza responses in aged mice

Age is the greatest risk factor for adverse outcomes following influenza (flu) infection. The increased burden of senescent cells with age has been identified as a root cause in many diseases of aging and targeting these cells with drugs termed senolytics has shown promise in alleviating many age-re...

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Detalles Bibliográficos
Autores principales: Torrance, Blake L., Cadar, Andreia N., Martin, Dominique E., Panier, Hunter A., Lorenzo, Erica C., Bartley, Jenna M., Xu, Ming, Haynes, Laura
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10313122/
https://www.ncbi.nlm.nih.gov/pubmed/37396956
http://dx.doi.org/10.3389/fragi.2023.1212750