Molecular portraits of cell cycle checkpoint kinases in cancer evolution, progression, and treatment responsiveness

Cell cycle dysregulation is prerequisite for cancer formation. However, it is unknown whether the mode of dysregulation affects disease characteristics. Here, we conduct comprehensive analyses of cell cycle checkpoint dysregulation using patient data and experimental investigations. We find that ATM...

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Detalles Bibliográficos
Autores principales: Oropeza, Elena, Seker, Sinem, Carrel, Sabrina, Mazumder, Aloran, Lozano, Daniel, Jimenez, Athena, VandenHeuvel, Sabrina N., Noltensmeyer, Dillon A., Punturi, Nindo B., Lei, Jonathan T., Lim, Bora, Waltz, Susan E., Raghavan, Shreya A., Bainbridge, Matthew N., Haricharan, Svasti
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2023
Materias:
Biomedicine and Life Sciences
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10313178/
https://www.ncbi.nlm.nih.gov/pubmed/37390209
http://dx.doi.org/10.1126/sciadv.adf2860

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