Nontuberculous mycobacteria in patients of a specialty hospital

The incidence and clinical characteristics of NTM diseases in Brazil remain relatively unknown. The present study describes the diagnosis of NTM isolates, the clinical presentation and treatment outcomes. We analyzed NTM isolates in patients of a tertiary hospital in the Southeast region of Brazil,...

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Detalles Bibliográficos
Autores principales: Barboza, Grazielle Conceição Sousa, de Almeida, Isabela Neves, dos Santos, Lucas Benício, Augusto, Claudio José, Leal, Élida Aparecida, de Pádua, Cristiane Aparecida Menezes, Cesar, Aina Liz Alves, Kritski, Afrânio Lineu, Carvalho, Wânia da Silva, de Miranda, Silvana Spíndola, Figueredo, Lida Jouca de Assis
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Instituto de Medicina Tropical de São Paulo 2023
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10313315/
https://www.ncbi.nlm.nih.gov/pubmed/37403880
http://dx.doi.org/10.1590/S1678-9946202365042
Descripción
Sumario:The incidence and clinical characteristics of NTM diseases in Brazil remain relatively unknown. The present study describes the diagnosis of NTM isolates, the clinical presentation and treatment outcomes. We analyzed NTM isolates in patients of a tertiary hospital in the Southeast region of Brazil, from January 2008 to July 2019. The ATS/IDSA criteria for diagnosis and treatment of these patients was applied. Mycobacterium kansasii were identified in 13/113 (11.5%) patients. In 59/113 (52.2%) patients who met the ATS criteria for disease, 29/59 (49.1%) received treatment, and 22/29 (75.8%) were cured. The major species identified was M. kansasii. The most frequent symptoms among the treated patients were dyspnea and cough, and the proportion of cured patients was high.

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