Nontuberculous mycobacteria in patients of a specialty hospital

The incidence and clinical characteristics of NTM diseases in Brazil remain relatively unknown. The present study describes the diagnosis of NTM isolates, the clinical presentation and treatment outcomes. We analyzed NTM isolates in patients of a tertiary hospital in the Southeast region of Brazil,...

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Autores principales: Barboza, Grazielle Conceição Sousa, de Almeida, Isabela Neves, dos Santos, Lucas Benício, Augusto, Claudio José, Leal, Élida Aparecida, de Pádua, Cristiane Aparecida Menezes, Cesar, Aina Liz Alves, Kritski, Afrânio Lineu, Carvalho, Wânia da Silva, de Miranda, Silvana Spíndola, Figueredo, Lida Jouca de Assis
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Instituto de Medicina Tropical de São Paulo 2023
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10313315/
https://www.ncbi.nlm.nih.gov/pubmed/37403880
http://dx.doi.org/10.1590/S1678-9946202365042
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author Barboza, Grazielle Conceição Sousa
de Almeida, Isabela Neves
dos Santos, Lucas Benício
Augusto, Claudio José
Leal, Élida Aparecida
de Pádua, Cristiane Aparecida Menezes
Cesar, Aina Liz Alves
Kritski, Afrânio Lineu
Carvalho, Wânia da Silva
de Miranda, Silvana Spíndola
Figueredo, Lida Jouca de Assis
author_facet Barboza, Grazielle Conceição Sousa
de Almeida, Isabela Neves
dos Santos, Lucas Benício
Augusto, Claudio José
Leal, Élida Aparecida
de Pádua, Cristiane Aparecida Menezes
Cesar, Aina Liz Alves
Kritski, Afrânio Lineu
Carvalho, Wânia da Silva
de Miranda, Silvana Spíndola
Figueredo, Lida Jouca de Assis
author_sort Barboza, Grazielle Conceição Sousa
collection PubMed
description The incidence and clinical characteristics of NTM diseases in Brazil remain relatively unknown. The present study describes the diagnosis of NTM isolates, the clinical presentation and treatment outcomes. We analyzed NTM isolates in patients of a tertiary hospital in the Southeast region of Brazil, from January 2008 to July 2019. The ATS/IDSA criteria for diagnosis and treatment of these patients was applied. Mycobacterium kansasii were identified in 13/113 (11.5%) patients. In 59/113 (52.2%) patients who met the ATS criteria for disease, 29/59 (49.1%) received treatment, and 22/29 (75.8%) were cured. The major species identified was M. kansasii. The most frequent symptoms among the treated patients were dyspnea and cough, and the proportion of cured patients was high.
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spelling pubmed-103133152023-07-01 Nontuberculous mycobacteria in patients of a specialty hospital Barboza, Grazielle Conceição Sousa de Almeida, Isabela Neves dos Santos, Lucas Benício Augusto, Claudio José Leal, Élida Aparecida de Pádua, Cristiane Aparecida Menezes Cesar, Aina Liz Alves Kritski, Afrânio Lineu Carvalho, Wânia da Silva de Miranda, Silvana Spíndola Figueredo, Lida Jouca de Assis Rev Inst Med Trop Sao Paulo Original Article The incidence and clinical characteristics of NTM diseases in Brazil remain relatively unknown. The present study describes the diagnosis of NTM isolates, the clinical presentation and treatment outcomes. We analyzed NTM isolates in patients of a tertiary hospital in the Southeast region of Brazil, from January 2008 to July 2019. The ATS/IDSA criteria for diagnosis and treatment of these patients was applied. Mycobacterium kansasii were identified in 13/113 (11.5%) patients. In 59/113 (52.2%) patients who met the ATS criteria for disease, 29/59 (49.1%) received treatment, and 22/29 (75.8%) were cured. The major species identified was M. kansasii. The most frequent symptoms among the treated patients were dyspnea and cough, and the proportion of cured patients was high. Instituto de Medicina Tropical de São Paulo 2023-06-30 /pmc/articles/PMC10313315/ /pubmed/37403880 http://dx.doi.org/10.1590/S1678-9946202365042 Text en https://creativecommons.org/licenses/by-nc/4.0/ This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License, which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Original Article
Barboza, Grazielle Conceição Sousa
de Almeida, Isabela Neves
dos Santos, Lucas Benício
Augusto, Claudio José
Leal, Élida Aparecida
de Pádua, Cristiane Aparecida Menezes
Cesar, Aina Liz Alves
Kritski, Afrânio Lineu
Carvalho, Wânia da Silva
de Miranda, Silvana Spíndola
Figueredo, Lida Jouca de Assis
Nontuberculous mycobacteria in patients of a specialty hospital
title Nontuberculous mycobacteria in patients of a specialty hospital
title_full Nontuberculous mycobacteria in patients of a specialty hospital
title_fullStr Nontuberculous mycobacteria in patients of a specialty hospital
title_full_unstemmed Nontuberculous mycobacteria in patients of a specialty hospital
title_short Nontuberculous mycobacteria in patients of a specialty hospital
title_sort nontuberculous mycobacteria in patients of a specialty hospital
topic Original Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10313315/
https://www.ncbi.nlm.nih.gov/pubmed/37403880
http://dx.doi.org/10.1590/S1678-9946202365042
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