iPSC-derived reactive astrocytes from patients with multiple sclerosis protect cocultured neurons in inflammatory conditions

Multiple sclerosis (MS) is the most common chronic central nervous system inflammatory disease. Individual courses are highly variable, with complete remission in some patients and relentless progression in others. We generated induced pluripotent stem cells (iPSCs) to investigate possible mechanism...

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Detalles Bibliográficos
Autores principales: Kerkering, Janis, Muinjonov, Bakhrom, Rosiewicz, Kamil S., Diecke, Sebastian, Biese, Charlotte, Schiweck, Juliane, Chien, Claudia, Zocholl, Dario, Conrad, Thomas, Paul, Friedemann, Alisch, Marlen, Siffrin, Volker
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Clinical Investigation 2023
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10313373/
https://www.ncbi.nlm.nih.gov/pubmed/37219933
http://dx.doi.org/10.1172/JCI164637

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