Tumor-activated lymph node fibroblasts suppress T cell function in diffuse large B cell lymphoma

Recent transcriptomic-based analysis of diffuse large B cell lymphoma (DLBCL) has highlighted the clinical relevance of LN fibroblast and tumor-infiltrating lymphocyte (TIL) signatures within the tumor microenvironment (TME). However, the immunomodulatory role of fibroblasts in lymphoma remains uncl...

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Detalles Bibliográficos
Autores principales: Apollonio, Benedetta, Spada, Filomena, Petrov, Nedyalko, Cozzetto, Domenico, Papazoglou, Despoina, Jarvis, Peter, Kannambath, Shichina, Terranova-Barberio, Manuela, Amini, Rose-Marie, Enblad, Gunilla, Graham, Charlotte, Benjamin, Reuben, Phillips, Elisabeth, Ellis, Richard, Nuamah, Rosamond, Saqi, Mansoor, Calado, Dinis P., Rosenquist, Richard, Sutton, Lesley A., Salisbury, Jon, Zacharioudakis, Georgios, Vardi, Anna, Hagner, Patrick R., Gandhi, Anita K., Bacac, Marina, Claus, Christina, Umana, Pablo, Jarrett, Ruth F., Klein, Christian, Deutsch, Alexander, Ramsay, Alan G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Clinical Investigation 2023
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10313378/
https://www.ncbi.nlm.nih.gov/pubmed/37219943
http://dx.doi.org/10.1172/JCI166070

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