Mature Teratoma with Somatic-Type Malignancy: An Entity of Unacquaintance—A Case Report

Primary intracranial teratomas are nongerminomatous germ cell tumors. They are infrequent lesions along the craniospinal axis, with their malignant transformation extremely uncommon. A 50-year-old-male patient presented with one episode of generalized tonic–clonic seizure (GTCS), without any neurolo...

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Autores principales: Diyora, Batuk, Devani, Kavin, Epari, Sridhar, Deshpande, Gauri, Purandare, Anup, Wankhade, Ravi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Thieme Medical and Scientific Publishers Pvt. Ltd. 2023
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10313429/
https://www.ncbi.nlm.nih.gov/pubmed/37397059
http://dx.doi.org/10.1055/s-0043-1768603
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author Diyora, Batuk
Devani, Kavin
Epari, Sridhar
Deshpande, Gauri
Purandare, Anup
Wankhade, Ravi
author_facet Diyora, Batuk
Devani, Kavin
Epari, Sridhar
Deshpande, Gauri
Purandare, Anup
Wankhade, Ravi
author_sort Diyora, Batuk
collection PubMed
description Primary intracranial teratomas are nongerminomatous germ cell tumors. They are infrequent lesions along the craniospinal axis, with their malignant transformation extremely uncommon. A 50-year-old-male patient presented with one episode of generalized tonic–clonic seizure (GTCS), without any neurological deficit. Radiological imaging revealed a large lesion in the pineal region. He underwent gross total excision of the lesion. Histopathological examination was representative of teratoma with adenocarcinomatous malignant transformation. He underwent adjuvant radiation therapy and had an excellent clinical outcome. The present case highlights the rarity of malignant transformation of the primary intracranial mature teratoma.
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spelling pubmed-103134292023-07-01 Mature Teratoma with Somatic-Type Malignancy: An Entity of Unacquaintance—A Case Report Diyora, Batuk Devani, Kavin Epari, Sridhar Deshpande, Gauri Purandare, Anup Wankhade, Ravi Asian J Neurosurg Primary intracranial teratomas are nongerminomatous germ cell tumors. They are infrequent lesions along the craniospinal axis, with their malignant transformation extremely uncommon. A 50-year-old-male patient presented with one episode of generalized tonic–clonic seizure (GTCS), without any neurological deficit. Radiological imaging revealed a large lesion in the pineal region. He underwent gross total excision of the lesion. Histopathological examination was representative of teratoma with adenocarcinomatous malignant transformation. He underwent adjuvant radiation therapy and had an excellent clinical outcome. The present case highlights the rarity of malignant transformation of the primary intracranial mature teratoma. Thieme Medical and Scientific Publishers Pvt. Ltd. 2023-06-07 /pmc/articles/PMC10313429/ /pubmed/37397059 http://dx.doi.org/10.1055/s-0043-1768603 Text en Asian Congress of Neurological Surgeons. This is an open access article published by Thieme under the terms of the Creative Commons Attribution-NonDerivative-NonCommercial License, permitting copying and reproduction so long as the original work is given appropriate credit. Contents may not be used for commercial purposes, or adapted, remixed, transformed or built upon. ( https://creativecommons.org/licenses/by-nc-nd/4.0/ ) https://creativecommons.org/licenses/by-nc-nd/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivatives License, which permits unrestricted reproduction and distribution, for non-commercial purposes only; and use and reproduction, but not distribution, of adapted material for non-commercial purposes only, provided the original work is properly cited.
spellingShingle Diyora, Batuk
Devani, Kavin
Epari, Sridhar
Deshpande, Gauri
Purandare, Anup
Wankhade, Ravi
Mature Teratoma with Somatic-Type Malignancy: An Entity of Unacquaintance—A Case Report
title Mature Teratoma with Somatic-Type Malignancy: An Entity of Unacquaintance—A Case Report
title_full Mature Teratoma with Somatic-Type Malignancy: An Entity of Unacquaintance—A Case Report
title_fullStr Mature Teratoma with Somatic-Type Malignancy: An Entity of Unacquaintance—A Case Report
title_full_unstemmed Mature Teratoma with Somatic-Type Malignancy: An Entity of Unacquaintance—A Case Report
title_short Mature Teratoma with Somatic-Type Malignancy: An Entity of Unacquaintance—A Case Report
title_sort mature teratoma with somatic-type malignancy: an entity of unacquaintance—a case report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10313429/
https://www.ncbi.nlm.nih.gov/pubmed/37397059
http://dx.doi.org/10.1055/s-0043-1768603
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