Cardiac Sarcoidosis and a Likely Pathogenic TTN Variant in a Patient Presenting With Ventricular Tachycardia

Rare variants in TTN are the most common monogenic cause of early-onset atrial fibrillation and dilated cardiomyopathy. Whereas cardiac sarcoidosis is very underdiagnosed, a common presentation can be ventricular arrhythmias. This report presents a patient with a likely pathogenic TTN variant and ca...

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Autores principales: Virk, Zain M., Richardson, T. Lee, Nowatzke, Joseph F., Ullah, Asad, Pedrotty, Dawn M., Shoemaker, M. Benjamin, Kanagasundram, Arvindh, Roden, Dan M., Stevenson, William G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10313492/
https://www.ncbi.nlm.nih.gov/pubmed/37396334
http://dx.doi.org/10.1016/j.jaccas.2023.101878
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author Virk, Zain M.
Richardson, T. Lee
Nowatzke, Joseph F.
Ullah, Asad
Pedrotty, Dawn M.
Shoemaker, M. Benjamin
Kanagasundram, Arvindh
Roden, Dan M.
Stevenson, William G.
author_facet Virk, Zain M.
Richardson, T. Lee
Nowatzke, Joseph F.
Ullah, Asad
Pedrotty, Dawn M.
Shoemaker, M. Benjamin
Kanagasundram, Arvindh
Roden, Dan M.
Stevenson, William G.
author_sort Virk, Zain M.
collection PubMed
description Rare variants in TTN are the most common monogenic cause of early-onset atrial fibrillation and dilated cardiomyopathy. Whereas cardiac sarcoidosis is very underdiagnosed, a common presentation can be ventricular arrhythmias. This report presents a patient with a likely pathogenic TTN variant and cardiac sarcoidosis. (Level of Difficulty: Intermediate.)
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spelling pubmed-103134922023-07-01 Cardiac Sarcoidosis and a Likely Pathogenic TTN Variant in a Patient Presenting With Ventricular Tachycardia Virk, Zain M. Richardson, T. Lee Nowatzke, Joseph F. Ullah, Asad Pedrotty, Dawn M. Shoemaker, M. Benjamin Kanagasundram, Arvindh Roden, Dan M. Stevenson, William G. JACC Case Rep Case Report Rare variants in TTN are the most common monogenic cause of early-onset atrial fibrillation and dilated cardiomyopathy. Whereas cardiac sarcoidosis is very underdiagnosed, a common presentation can be ventricular arrhythmias. This report presents a patient with a likely pathogenic TTN variant and cardiac sarcoidosis. (Level of Difficulty: Intermediate.) Elsevier 2023-05-17 /pmc/articles/PMC10313492/ /pubmed/37396334 http://dx.doi.org/10.1016/j.jaccas.2023.101878 Text en © 2023 The Authors https://creativecommons.org/licenses/by-nc-nd/4.0/This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).
spellingShingle Case Report
Virk, Zain M.
Richardson, T. Lee
Nowatzke, Joseph F.
Ullah, Asad
Pedrotty, Dawn M.
Shoemaker, M. Benjamin
Kanagasundram, Arvindh
Roden, Dan M.
Stevenson, William G.
Cardiac Sarcoidosis and a Likely Pathogenic TTN Variant in a Patient Presenting With Ventricular Tachycardia
title Cardiac Sarcoidosis and a Likely Pathogenic TTN Variant in a Patient Presenting With Ventricular Tachycardia
title_full Cardiac Sarcoidosis and a Likely Pathogenic TTN Variant in a Patient Presenting With Ventricular Tachycardia
title_fullStr Cardiac Sarcoidosis and a Likely Pathogenic TTN Variant in a Patient Presenting With Ventricular Tachycardia
title_full_unstemmed Cardiac Sarcoidosis and a Likely Pathogenic TTN Variant in a Patient Presenting With Ventricular Tachycardia
title_short Cardiac Sarcoidosis and a Likely Pathogenic TTN Variant in a Patient Presenting With Ventricular Tachycardia
title_sort cardiac sarcoidosis and a likely pathogenic ttn variant in a patient presenting with ventricular tachycardia
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10313492/
https://www.ncbi.nlm.nih.gov/pubmed/37396334
http://dx.doi.org/10.1016/j.jaccas.2023.101878
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