Cargando…
Predicting the pathological invasiveness of early lung adenocarcinoma prior to surgery using Deauville criteria: reliability and validity
PURPOSE: This retrospective study aimed to investigate the validity and reliability of FDG-PET/CT visual assessment using Deauville criteria to predict pathological invasiveness of early lung adenocarcinoma prior to surgery. MATERIALS AND METHODS: Between April 2020 and January 2022, 51 patients who...
Autores principales: | , , , , , , , , , , , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer Nature Singapore
2023
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10313578/ https://www.ncbi.nlm.nih.gov/pubmed/36752955 http://dx.doi.org/10.1007/s11604-023-01397-z |
_version_ | 1785067156383203328 |
---|---|
author | Nishimori, Miki Iwasa, Hitomi Nakaji, Kosuke Nitta, Noriko Miyatake, Kana Yoshimatsu, Rika Yamanishi, Tomoaki Matsumoto, Tomohiro Kato, Mahiru Hayashi, Naoya Toi, Makoto Tamura, Masaya Yamagami, Takuji |
author_facet | Nishimori, Miki Iwasa, Hitomi Nakaji, Kosuke Nitta, Noriko Miyatake, Kana Yoshimatsu, Rika Yamanishi, Tomoaki Matsumoto, Tomohiro Kato, Mahiru Hayashi, Naoya Toi, Makoto Tamura, Masaya Yamagami, Takuji |
author_sort | Nishimori, Miki |
collection | PubMed |
description | PURPOSE: This retrospective study aimed to investigate the validity and reliability of FDG-PET/CT visual assessment using Deauville criteria to predict pathological invasiveness of early lung adenocarcinoma prior to surgery. MATERIALS AND METHODS: Between April 2020 and January 2022, 51 patients who underwent surgery for pathological stage 0/I lung adenocarcinoma were enrolled. The pulmonary lesions were divided into two groups according to pathological invasiveness: less invasive (including adenocarcinoma in situ and minimally invasive adenocarcinoma and invasive adenocarcinoma. We compared CT size (total and solid size), SUVmax, and Deauville score between the two groups. Furthermore, we investigated inter-rater and intra-rater agreements regarding the Deauville score. Receiver operating characteristic (ROC) curve analysis was performed to identify the diagnostic performance of each method. RESULTS: Based on pathologic diagnoses, 51 lesions in the 51 patients were divided into 6 less invasive and 45 invasive adenocarcinoma lesions. According to quadratic-weighted Kappa statistics, inter-rater (k = 0.93) and intra-rater (k = 0.97) agreements among all five components of the Deauville score indicated high agreement. There was a statistically significant difference in CT solid size, SUVmax, and Deauville score between the two groups. There were no significant differences between CT solid size and FDG-PET/CT assessments (AUC = 0.93 for Deauville score and SUVmax, AUC = 0.84 for CT solid size). CONCLUSION: FDG-PET/CT visual assessment using the Deauville score could assist in deciding upon minimally invasive surgery for early lung adenocarcinoma. |
format | Online Article Text |
id | pubmed-10313578 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2023 |
publisher | Springer Nature Singapore |
record_format | MEDLINE/PubMed |
spelling | pubmed-103135782023-07-02 Predicting the pathological invasiveness of early lung adenocarcinoma prior to surgery using Deauville criteria: reliability and validity Nishimori, Miki Iwasa, Hitomi Nakaji, Kosuke Nitta, Noriko Miyatake, Kana Yoshimatsu, Rika Yamanishi, Tomoaki Matsumoto, Tomohiro Kato, Mahiru Hayashi, Naoya Toi, Makoto Tamura, Masaya Yamagami, Takuji Jpn J Radiol Original Article PURPOSE: This retrospective study aimed to investigate the validity and reliability of FDG-PET/CT visual assessment using Deauville criteria to predict pathological invasiveness of early lung adenocarcinoma prior to surgery. MATERIALS AND METHODS: Between April 2020 and January 2022, 51 patients who underwent surgery for pathological stage 0/I lung adenocarcinoma were enrolled. The pulmonary lesions were divided into two groups according to pathological invasiveness: less invasive (including adenocarcinoma in situ and minimally invasive adenocarcinoma and invasive adenocarcinoma. We compared CT size (total and solid size), SUVmax, and Deauville score between the two groups. Furthermore, we investigated inter-rater and intra-rater agreements regarding the Deauville score. Receiver operating characteristic (ROC) curve analysis was performed to identify the diagnostic performance of each method. RESULTS: Based on pathologic diagnoses, 51 lesions in the 51 patients were divided into 6 less invasive and 45 invasive adenocarcinoma lesions. According to quadratic-weighted Kappa statistics, inter-rater (k = 0.93) and intra-rater (k = 0.97) agreements among all five components of the Deauville score indicated high agreement. There was a statistically significant difference in CT solid size, SUVmax, and Deauville score between the two groups. There were no significant differences between CT solid size and FDG-PET/CT assessments (AUC = 0.93 for Deauville score and SUVmax, AUC = 0.84 for CT solid size). CONCLUSION: FDG-PET/CT visual assessment using the Deauville score could assist in deciding upon minimally invasive surgery for early lung adenocarcinoma. Springer Nature Singapore 2023-02-08 2023 /pmc/articles/PMC10313578/ /pubmed/36752955 http://dx.doi.org/10.1007/s11604-023-01397-z Text en © The Author(s) 2023 https://creativecommons.org/licenses/by/4.0/Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) . |
spellingShingle | Original Article Nishimori, Miki Iwasa, Hitomi Nakaji, Kosuke Nitta, Noriko Miyatake, Kana Yoshimatsu, Rika Yamanishi, Tomoaki Matsumoto, Tomohiro Kato, Mahiru Hayashi, Naoya Toi, Makoto Tamura, Masaya Yamagami, Takuji Predicting the pathological invasiveness of early lung adenocarcinoma prior to surgery using Deauville criteria: reliability and validity |
title | Predicting the pathological invasiveness of early lung adenocarcinoma prior to surgery using Deauville criteria: reliability and validity |
title_full | Predicting the pathological invasiveness of early lung adenocarcinoma prior to surgery using Deauville criteria: reliability and validity |
title_fullStr | Predicting the pathological invasiveness of early lung adenocarcinoma prior to surgery using Deauville criteria: reliability and validity |
title_full_unstemmed | Predicting the pathological invasiveness of early lung adenocarcinoma prior to surgery using Deauville criteria: reliability and validity |
title_short | Predicting the pathological invasiveness of early lung adenocarcinoma prior to surgery using Deauville criteria: reliability and validity |
title_sort | predicting the pathological invasiveness of early lung adenocarcinoma prior to surgery using deauville criteria: reliability and validity |
topic | Original Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10313578/ https://www.ncbi.nlm.nih.gov/pubmed/36752955 http://dx.doi.org/10.1007/s11604-023-01397-z |
work_keys_str_mv | AT nishimorimiki predictingthepathologicalinvasivenessofearlylungadenocarcinomapriortosurgeryusingdeauvillecriteriareliabilityandvalidity AT iwasahitomi predictingthepathologicalinvasivenessofearlylungadenocarcinomapriortosurgeryusingdeauvillecriteriareliabilityandvalidity AT nakajikosuke predictingthepathologicalinvasivenessofearlylungadenocarcinomapriortosurgeryusingdeauvillecriteriareliabilityandvalidity AT nittanoriko predictingthepathologicalinvasivenessofearlylungadenocarcinomapriortosurgeryusingdeauvillecriteriareliabilityandvalidity AT miyatakekana predictingthepathologicalinvasivenessofearlylungadenocarcinomapriortosurgeryusingdeauvillecriteriareliabilityandvalidity AT yoshimatsurika predictingthepathologicalinvasivenessofearlylungadenocarcinomapriortosurgeryusingdeauvillecriteriareliabilityandvalidity AT yamanishitomoaki predictingthepathologicalinvasivenessofearlylungadenocarcinomapriortosurgeryusingdeauvillecriteriareliabilityandvalidity AT matsumototomohiro predictingthepathologicalinvasivenessofearlylungadenocarcinomapriortosurgeryusingdeauvillecriteriareliabilityandvalidity AT katomahiru predictingthepathologicalinvasivenessofearlylungadenocarcinomapriortosurgeryusingdeauvillecriteriareliabilityandvalidity AT hayashinaoya predictingthepathologicalinvasivenessofearlylungadenocarcinomapriortosurgeryusingdeauvillecriteriareliabilityandvalidity AT toimakoto predictingthepathologicalinvasivenessofearlylungadenocarcinomapriortosurgeryusingdeauvillecriteriareliabilityandvalidity AT tamuramasaya predictingthepathologicalinvasivenessofearlylungadenocarcinomapriortosurgeryusingdeauvillecriteriareliabilityandvalidity AT yamagamitakuji predictingthepathologicalinvasivenessofearlylungadenocarcinomapriortosurgeryusingdeauvillecriteriareliabilityandvalidity |