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Interferon-γ elicits the ocular surface pathology mimicking dry eye through direct modulation of resident corneal cells

Despite accumulating evidence indicating a key role of interferon-γ (IFN-γ)-producing immune cells in ocular infection and immunity, little is known about the direct effects of IFN-γ on resident corneal cells or on the ocular surface. Here, we report that IFN-γ impacts corneal stromal fibroblasts an...

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Detalles Bibliográficos
Autores principales: Ko, Jung Hwa, Kim, Seonghwan, Ryu, Jin Suk, Song, Hyo Jeong, Oh, Joo Youn
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10313777/
https://www.ncbi.nlm.nih.gov/pubmed/37391421
http://dx.doi.org/10.1038/s41420-023-01511-0