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AAV9-Tspyl2 gene therapy retards bleomycin-induced pulmonary fibrosis by modulating downstream TGF-β signaling in mice

Idiopathic pulmonary fibrosis (IPF) is a devastating fibrotic lung disease characterized by scarring and destruction of the lung architecture, with limited treatment options. Targeted gene therapy to restore cell division autoantigen-1 (CDA1) expression may be a potential treatment approach to delay...

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Detalles Bibliográficos
Autores principales:	Zhang, Shijie, Tong, Xiang, Liu, Sitong, Huang, Jizhen, Zhang, Li, Zhang, Tianli, Wang, Dongguang, Fan, Hong
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2023
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10313802/ https://www.ncbi.nlm.nih.gov/pubmed/37391440 http://dx.doi.org/10.1038/s41419-023-05889-8

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