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Simulation study for evaluating an adaptive-randomisation Bayesian hybrid trial design with enrichment

BACKGROUND: As we enter the era of precision medicine, the role of adaptive designs, such as response-adaptive randomisation or enrichment designs in drug discovery and development, has become increasingly important to identify the treatment given to a patient based on one or more biomarkers. Tailor...

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Detalles Bibliográficos
Autores principales: Vinnat, Valentin, Chiche, Jean-Daniel, Demoule, Alexandre, Chevret, Sylvie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10313856/
https://www.ncbi.nlm.nih.gov/pubmed/37397429
http://dx.doi.org/10.1016/j.conctc.2023.101141