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Simulation study for evaluating an adaptive-randomisation Bayesian hybrid trial design with enrichment
BACKGROUND: As we enter the era of precision medicine, the role of adaptive designs, such as response-adaptive randomisation or enrichment designs in drug discovery and development, has become increasingly important to identify the treatment given to a patient based on one or more biomarkers. Tailor...
Autores principales: | Vinnat, Valentin, Chiche, Jean-Daniel, Demoule, Alexandre, Chevret, Sylvie |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10313856/ https://www.ncbi.nlm.nih.gov/pubmed/37397429 http://dx.doi.org/10.1016/j.conctc.2023.101141 |
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