Cargando…

An analytical framework for decoding cell type-specific genetic variation of gene regulation

A deeper understanding of genetic regulation and functional mechanisms underlying genetic associations with complex traits and diseases is impeded by cellular heterogeneity and linkage disequilibrium. To address these limits, we introduce Huatuo, a framework to decode genetic variation of gene regul...

Descripción completa

Detalles Bibliográficos
Autores principales:	Xiao, Yanyu, Wang, Jingjing, Li, Jiaqi, Zhang, Peijing, Li, Jingyu, Zhou, Yincong, Zhou, Qing, Chen, Ming, Sheng, Xin, Liu, Zhihong, Han, Xiaoping, Guo, Guoji
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2023
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10313894/ https://www.ncbi.nlm.nih.gov/pubmed/37391400 http://dx.doi.org/10.1038/s41467-023-39538-7

Ejemplares similares

Construction of the axolotl cell landscape using combinatorial hybridization sequencing at single-cell resolution
por: Ye, Fang, et al.
Publicado: (2022)

Publisher Correction: Cell landscape of larval and adult Xenopus laevis at single-cell resolution
por: Liao, Yuan, et al.
Publicado: (2022)

Cell landscape of larval and adult Xenopus laevis at single-cell resolution
por: Liao, Yuan, et al.
Publicado: (2022)

From musk to body odor: Decoding olfaction through genetic variation
por: Li, Bingjie, et al.
Publicado: (2022)

PlantCircNet: a database for plant circRNA–miRNA–mRNA regulatory networks
por: Zhang, Peijing, et al.
Publicado: (2017)

Meta-analytic decoding of the cortical gradient of functional connectivity
por: Peraza, Julio A., et al.
Publicado: (2023)

Comparison of Scanpy-based algorithms to remove the batch effect from single-cell RNA-seq data
por: Li, Jiaqi, et al.
Publicado: (2020)

Recent Analytical Advances for Decoding Metabolic Reprogramming in Lung Cancer
por: Almalki, Atiah H.
Publicado: (2023)

Nematode-specific tRNAs that decode an alternative genetic code for leucine
por: Hamashima, Kiyofumi, et al.
Publicado: (2012)

Unwarranted clinical variation in health care: Definitions and proposal of an analytic framework
por: Sutherland, Kim, et al.
Publicado: (2019)

Aerolysin nanopores decode digital information stored in tailored macromolecular analytes
por: Cao, Chan, et al.
Publicado: (2020)

A parameter-optimization framework for neural decoding systems
por: Xie, Jing, et al.
Publicado: (2023)

Efficacy of herbal medicine (cinnamon/fennel/ginger) for primary dysmenorrhea: a systematic review and meta-analysis of randomized controlled trials
por: Xu, Yincong, et al.
Publicado: (2020)

NetDecoder: a network biology platform that decodes context-specific biological networks and gene activities
por: da Rocha, Edroaldo Lummertz, et al.
Publicado: (2016)

Decoding genetic risks of heart disease
Publicado: (2019)

Editorial: Decoding the genetics of viral evolution
por: Ali, Hashim, et al.
Publicado: (2022)

Characterization of the Zebrafish Cell Landscape at Single-Cell Resolution
por: Jiang, Mengmeng, et al.
Publicado: (2021)

Decoding the role of TET family dioxygenases in lineage specification
por: Wu, Xinwei, et al.
Publicado: (2018)

Molecular decoding using luminescence from an entangled porous framework
por: Takashima, Yohei, et al.
Publicado: (2011)

Construction of a cross-species cell landscape at single-cell level
por: Wang, Renying, et al.
Publicado: (2022)

A Tensor-Product-Kernel Framework for Multiscale Neural Activity Decoding and Control
por: Li, Lin, et al.
Publicado: (2014)

Molecular Targets and Associated Signaling Pathways of Jingshu Granules in Ovarian Cysts Based on Systemic Pharmacological Analysis
por: Xu, Jili, et al.
Publicado: (2021)

Decoding the Mechanism behind the Pathogenesis of the Focal Segmental Glomerulosclerosis
por: Zhu, Xiao, et al.
Publicado: (2022)

Framework for interpretation of genetic variations in pancreatitis patients
por: Whitcomb, David C.
Publicado: (2012)

Steam turbine power prediction based on encode-decoder framework guided by the condenser vacuum degree
por: Lu, Yanning, et al.
Publicado: (2022)

An analytical framework for interpretable and generalizable single-cell data analysis
por: Zhou, Jian, et al.
Publicado: (2021)

In situ dissecting the evolution of gene duplication with different histone modification patterns based on high-throughput data analysis in Arabidopsis thaliana
por: Wang, Jingjing, et al.
Publicado: (2021)

Editorial: Decoding Brain Function Through Genetics
por: Toriumi, Kazuya, et al.
Publicado: (2022)

Editorial: Decoding the genetics of milk fat traits
por: Cao, Xiang, et al.
Publicado: (2022)

Decoding RAS isoform and codon-specific signalling
por: Newlaczyl, Anna U., et al.
Publicado: (2014)

Decoding Partner Specificity of Opioid Receptor Family
por: Barreto, Carlos A. V., et al.
Publicado: (2021)

An informatic framework for decoding protein complexes by top-down mass spectrometry
por: Skinner, Owen S., et al.
Publicado: (2016)

Decoding Cancer Evolution: Integrating Genetic and Non-Genetic Insights
por: Ashouri, Arghavan, et al.
Publicado: (2023)

Unlocking Genetic Profiles with a Programmable DNA‐Powered Decoding Circuit
por: Liu, Junlan, et al.
Publicado: (2023)

Transcriptional Approach for Decoding the Mechanism of rpoC Compensatory Mutations for the Fitness Cost in Rifampicin-Resistant Mycobacterium tuberculosis
por: Xu, Zhihong, et al.
Publicado: (2018)

Connectivity and Order: an Analytical Framework
por: Gaens, Bart, et al.
Publicado: (2023)

Errors in translational decoding: tRNA wobbling or misincorporation?
por: Ou, Xumin, et al.
Publicado: (2019)

PhenoModifier: a genetic modifier database for elucidating the genetic basis of human phenotypic variation
por: Sun, Hong, et al.
Publicado: (2020)

Decoding the integrated approach to yoga therapy: Qualitative evidence based conceptual framework
por: Villacres, Maria Del Carmen, et al.
Publicado: (2014)

A Probabilistic Framework for Decoding Behavior From in vivo Calcium Imaging Data
por: Etter, Guillaume, et al.
Publicado: (2020)

Cannot write session to /tmp/vufind_sessions/sess_5o1kanbac25alc8oarkbng4svr