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Spatial and temporal intra-tumoral heterogeneity in advanced HGSOC: Implications for surgical and clinical outcomes

Limited evidence exists on the impact of spatial and temporal heterogeneity of high-grade serous ovarian cancer (HGSOC) on tumor evolution, clinical outcomes, and surgical operability. We perform systematic multi-site tumor mapping at presentation and matched relapse from 49 high-tumor-burden patien...

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Detalles Bibliográficos
Autores principales:	Cunnea, Paula, Curry, Edward W., Christie, Elizabeth L., Nixon, Katherine, Kwok, Chun Hei, Pandey, Ahwan, Wulandari, Ratri, Thol, Kerstin, Ploski, Jennifer, Morera-Albert, Cristina, McQuaid, Stephen, Lozano-Kuehne, Jingky, Clark, James J., Krell, Jonathan, Stronach, Euan A., McNeish, Iain A., Bowtell, David D.L., Fotopoulou, Christina
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2023
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10313917/ https://www.ncbi.nlm.nih.gov/pubmed/37220750 http://dx.doi.org/10.1016/j.xcrm.2023.101055

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