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Tissue-resident memory CAR T cells with stem-like characteristics display enhanced efficacy against solid and liquid tumors

Chimeric antigen receptor (CAR) T cells demonstrate remarkable success in treating hematological malignancies, but their effectiveness in non-hematopoietic cancers remains limited. This study proposes enhancing CAR T cell function and localization in solid tumors by modifying the epigenome governing...

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Detalles Bibliográficos
Autores principales:	Jung, In-Young, Noguera-Ortega, Estela, Bartoszek, Robert, Collins, Sierra M., Williams, Erik, Davis, Megan, Jadlowsky, Julie K., Plesa, Gabriela, Siegel, Donald L., Chew, Anne, Levine, Bruce L., Berger, Shelley L., Moon, Edmund K., Albelda, Steven M., Fraietta, Joseph A.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2023
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10313923/ https://www.ncbi.nlm.nih.gov/pubmed/37224816 http://dx.doi.org/10.1016/j.xcrm.2023.101053

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