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Steering CAR T cell epigenetic programs by tweaking manufacturing protocol
CAR T cell persistence remains a significant roadblock to effective clinical translation of CAR T cells for solid and brain tumors. Jung et al.(1) demonstrate enrichment of resident memory phenotypes through simple changes to the CAR T cell manufacturing process.
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Elsevier
2023
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10313927/ https://www.ncbi.nlm.nih.gov/pubmed/37343521 http://dx.doi.org/10.1016/j.xcrm.2023.101080 |