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Arginine depletion attenuates renal cystogenesis in tuberous sclerosis complex model

Cystic kidney disease is a leading cause of morbidity in patients with tuberous sclerosis complex (TSC). We characterize the misregulated metabolic pathways using cell lines, a TSC mouse model, and human kidney sections. Our study reveals a substantial perturbation in the arginine biosynthesis pathw...

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Detalles Bibliográficos
Autores principales:	Amleh, Athar, Chen, Hadass Pri, Watad, Lana, Abramovich, Ifat, Agranovich, Bella, Gottlieb, Eyal, Ben-Dov, Iddo Z., Nechama, Morris, Volovelsky, Oded
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2023
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10313931/ https://www.ncbi.nlm.nih.gov/pubmed/37290438 http://dx.doi.org/10.1016/j.xcrm.2023.101073

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