Plasma inflammation for predicting phenotypic conversion and clinical progression of autosomal dominant frontotemporal lobar degeneration

BACKGROUND: Measuring systemic inflammatory markers may improve clinical prognosis and help identify targetable pathways for treatment in patients with autosomal dominant forms of frontotemporal lobar degeneration (FTLD). METHODS: We measured plasma concentrations of IL-6, TNFα and YKL-40 in pathoge...

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Detalles Bibliográficos
Autores principales: Asken, Breton M, Ljubenkov, Peter A, Staffaroni, Adam M, Casaletto, Kaitlin B, Vandevrede, Lawren, Cobigo, Yann, Rojas-Rodriguez, Julio C, Rankin, Katherine P, Kornak, John, Heuer, Hilary, Shigenaga, Judy, Appleby, Brian S, Bozoki, Andrea C, Domoto-Reilly, Kimiko, Ghoshal, Nupur, Huey, Edward, Litvan, Irene, Masdeu, Joseph C, Mendez, Mario F, Pascual, Belen, Pressman, Peter, Tartaglia, Maria Carmela, Kremers, Walter, Forsberg, Leah K, Boeve, Brad F, Boxer, Adam L, Rosen, Howie J, Kramer, Joel H
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Publishing Group 2023
Materias:
Neurodegeneration
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10313977/
https://www.ncbi.nlm.nih.gov/pubmed/36977552
http://dx.doi.org/10.1136/jnnp-2022-330866

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