GSN gene frameshift mutations in Alzheimer’s disease

BACKGROUND: The pathogenic missense mutations of the gelsolin (GSN) gene lead to familial amyloidosis of the Finnish type (FAF); however, our previous study identified GSN frameshift mutations existed in patients with Alzheimer’s disease (AD). The GSN genotype–phenotype heterogeneity and the role of...

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Detalles Bibliográficos
Autores principales: Jiang, Yaling, Wan, Meidan, Xiao, XueWen, Lin, Zhuojie, Liu, Xixi, Zhou, Yafang, Liao, Xinxin, Lin, Jingyi, Zhou, Hui, Zhou, Lu, Weng, Ling, Wang, Junling, Guo, Jifeng, Jiang, Hong, Zhang, Zhuohua, Xia, Kun, Li, Jiada, Tang, Beisha, Jiao, Bin, Shen, Lu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Publishing Group 2023
Materias:
Neurodegeneration
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10314070/
https://www.ncbi.nlm.nih.gov/pubmed/36650038
http://dx.doi.org/10.1136/jnnp-2022-330465

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