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Ethical analysis examining the prioritisation of living donor transplantation in times of healthcare rationing
The transplant community has faced unprecedented challenges balancing risks of performing living donor transplants during the COVID-19 pandemic with harms of temporarily suspending these procedures. Decisions regarding postponement of living donation stem from its designation as an elective procedur...
Autores principales: | , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BMJ Publishing Group
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10314075/ https://www.ncbi.nlm.nih.gov/pubmed/34983855 http://dx.doi.org/10.1136/medethics-2021-107574 |
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author | Kulkarni, Sanjay Flescher, Andrew Ahmad, Mahwish Bayliss, George Bearl, David Biondi, Lynsey Davis, Earnest George, Roshan Gordon, Elisa Lyons, Tania Wightman, Aaron Ladin, Keren |
author_facet | Kulkarni, Sanjay Flescher, Andrew Ahmad, Mahwish Bayliss, George Bearl, David Biondi, Lynsey Davis, Earnest George, Roshan Gordon, Elisa Lyons, Tania Wightman, Aaron Ladin, Keren |
author_sort | Kulkarni, Sanjay |
collection | PubMed |
description | The transplant community has faced unprecedented challenges balancing risks of performing living donor transplants during the COVID-19 pandemic with harms of temporarily suspending these procedures. Decisions regarding postponement of living donation stem from its designation as an elective procedure, this despite that the Centers for Medicare and Medicaid Services categorise transplant procedures as tier 3b (high medical urgency—do not postpone). In times of severe resource constraints, health systems may be operating under crisis or contingency standards of care. In this manuscript, the United Network for Organ Sharing Ethics Workgroup explores prioritisation of living donation where health systems operate under contingency standards of care and provide a framework with recommendations to the transplant community on how to approach living donation in these circumstances. To guide the transplant community in future decisions, this analysis suggests that: (1) living donor transplants represent an important option for individuals with end-stage liver and kidney disease and should not be suspended uniformly under contingency standards, (2) exposure risk to SARS-CoV-2 should be balanced with other risks, such as exposure risks at dialysis centres. Because many of these risks are not quantifiable, donors and recipients should be included in discussions on what constitutes acceptable risk, (3) transplant hospitals should strive to maintain a critical transplant workforce and avoid diverting expertise, which could negatively impact patient preparedness for transplant, (4) transplant hospitals should consider implementing protocols to ensure early detection of SARS-CoV-2 infections and discuss these measures with donors and recipients in a process of shared decision-making. |
format | Online Article Text |
id | pubmed-10314075 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2023 |
publisher | BMJ Publishing Group |
record_format | MEDLINE/PubMed |
spelling | pubmed-103140752023-07-02 Ethical analysis examining the prioritisation of living donor transplantation in times of healthcare rationing Kulkarni, Sanjay Flescher, Andrew Ahmad, Mahwish Bayliss, George Bearl, David Biondi, Lynsey Davis, Earnest George, Roshan Gordon, Elisa Lyons, Tania Wightman, Aaron Ladin, Keren J Med Ethics Current Controversy The transplant community has faced unprecedented challenges balancing risks of performing living donor transplants during the COVID-19 pandemic with harms of temporarily suspending these procedures. Decisions regarding postponement of living donation stem from its designation as an elective procedure, this despite that the Centers for Medicare and Medicaid Services categorise transplant procedures as tier 3b (high medical urgency—do not postpone). In times of severe resource constraints, health systems may be operating under crisis or contingency standards of care. In this manuscript, the United Network for Organ Sharing Ethics Workgroup explores prioritisation of living donation where health systems operate under contingency standards of care and provide a framework with recommendations to the transplant community on how to approach living donation in these circumstances. To guide the transplant community in future decisions, this analysis suggests that: (1) living donor transplants represent an important option for individuals with end-stage liver and kidney disease and should not be suspended uniformly under contingency standards, (2) exposure risk to SARS-CoV-2 should be balanced with other risks, such as exposure risks at dialysis centres. Because many of these risks are not quantifiable, donors and recipients should be included in discussions on what constitutes acceptable risk, (3) transplant hospitals should strive to maintain a critical transplant workforce and avoid diverting expertise, which could negatively impact patient preparedness for transplant, (4) transplant hospitals should consider implementing protocols to ensure early detection of SARS-CoV-2 infections and discuss these measures with donors and recipients in a process of shared decision-making. BMJ Publishing Group 2023-06 2022-01-04 /pmc/articles/PMC10314075/ /pubmed/34983855 http://dx.doi.org/10.1136/medethics-2021-107574 Text en © Author(s) (or their employer(s)) 2023. Re-use permitted under CC BY. Published by BMJ. https://creativecommons.org/licenses/by/4.0/This is an open access article distributed in accordance with the Creative Commons Attribution 4.0 Unported (CC BY 4.0) license, which permits others to copy, redistribute, remix, transform and build upon this work for any purpose, provided the original work is properly cited, a link to the licence is given, and indication of whether changes were made. See: https://creativecommons.org/licenses/by/4.0/. |
spellingShingle | Current Controversy Kulkarni, Sanjay Flescher, Andrew Ahmad, Mahwish Bayliss, George Bearl, David Biondi, Lynsey Davis, Earnest George, Roshan Gordon, Elisa Lyons, Tania Wightman, Aaron Ladin, Keren Ethical analysis examining the prioritisation of living donor transplantation in times of healthcare rationing |
title | Ethical analysis examining the prioritisation of living donor transplantation in times of healthcare rationing |
title_full | Ethical analysis examining the prioritisation of living donor transplantation in times of healthcare rationing |
title_fullStr | Ethical analysis examining the prioritisation of living donor transplantation in times of healthcare rationing |
title_full_unstemmed | Ethical analysis examining the prioritisation of living donor transplantation in times of healthcare rationing |
title_short | Ethical analysis examining the prioritisation of living donor transplantation in times of healthcare rationing |
title_sort | ethical analysis examining the prioritisation of living donor transplantation in times of healthcare rationing |
topic | Current Controversy |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10314075/ https://www.ncbi.nlm.nih.gov/pubmed/34983855 http://dx.doi.org/10.1136/medethics-2021-107574 |
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