Organoids as a tool in drug discovery and patient-specific therapy for head and neck cancer

Organoids more accurately reflect tumor microenvironment than traditional models. Millen et al. demonstrated organoids replicated from patient tissues may predict patient-specific response to radiation therapy and have potential to be utilized for validation of biomarkers in drug discovery and treat...

Descripción completa

Detalles Bibliográficos
Autores principales: Done, Aaron J., Birkeland, Andrew C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Spotlight
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10314095/
https://www.ncbi.nlm.nih.gov/pubmed/37343518
http://dx.doi.org/10.1016/j.xcrm.2023.101087
_version_ 1785067249303814144
author Done, Aaron J.
Birkeland, Andrew C.
author_facet Done, Aaron J.
Birkeland, Andrew C.
author_sort Done, Aaron J.
collection PubMed
description Organoids more accurately reflect tumor microenvironment than traditional models. Millen et al. demonstrated organoids replicated from patient tissues may predict patient-specific response to radiation therapy and have potential to be utilized for validation of biomarkers in drug discovery and treatment planning.
format Online
Article
Text
id pubmed-10314095
institution National Center for Biotechnology Information
language English
publishDate 2023
publisher Elsevier
record_format MEDLINE/PubMed
spelling pubmed-103140952023-07-02 Organoids as a tool in drug discovery and patient-specific therapy for head and neck cancer Done, Aaron J. Birkeland, Andrew C. Cell Rep Med Spotlight Organoids more accurately reflect tumor microenvironment than traditional models. Millen et al. demonstrated organoids replicated from patient tissues may predict patient-specific response to radiation therapy and have potential to be utilized for validation of biomarkers in drug discovery and treatment planning. Elsevier 2023-06-20 /pmc/articles/PMC10314095/ /pubmed/37343518 http://dx.doi.org/10.1016/j.xcrm.2023.101087 Text en © 2023 The Authors https://creativecommons.org/licenses/by-nc-nd/4.0/This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).
spellingShingle Spotlight
Done, Aaron J.
Birkeland, Andrew C.
Organoids as a tool in drug discovery and patient-specific therapy for head and neck cancer
title Organoids as a tool in drug discovery and patient-specific therapy for head and neck cancer
title_full Organoids as a tool in drug discovery and patient-specific therapy for head and neck cancer
title_fullStr Organoids as a tool in drug discovery and patient-specific therapy for head and neck cancer
title_full_unstemmed Organoids as a tool in drug discovery and patient-specific therapy for head and neck cancer
title_short Organoids as a tool in drug discovery and patient-specific therapy for head and neck cancer
title_sort organoids as a tool in drug discovery and patient-specific therapy for head and neck cancer
topic Spotlight
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10314095/
https://www.ncbi.nlm.nih.gov/pubmed/37343518
http://dx.doi.org/10.1016/j.xcrm.2023.101087
work_keys_str_mv AT doneaaronj organoidsasatoolindrugdiscoveryandpatientspecifictherapyforheadandneckcancer
AT birkelandandrewc organoidsasatoolindrugdiscoveryandpatientspecifictherapyforheadandneckcancer

Ejemplares similares