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Tailored ASD destabilization - Balancing shelf life stability and dissolution performance with hydroxypropyl cellulose
Amorphous solid dispersion (ASD) formulations are preferred enabling formulations for poorly water soluble active pharmaceutical ingredients (API) as they reliably enhance the dissolution behavior and solubility. Balancing a high stability against unwanted transformations such as crystallization and...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10314205/ https://www.ncbi.nlm.nih.gov/pubmed/37396620 http://dx.doi.org/10.1016/j.ijpx.2023.100187 |