Cargando…

Tailored ASD destabilization - Balancing shelf life stability and dissolution performance with hydroxypropyl cellulose

Amorphous solid dispersion (ASD) formulations are preferred enabling formulations for poorly water soluble active pharmaceutical ingredients (API) as they reliably enhance the dissolution behavior and solubility. Balancing a high stability against unwanted transformations such as crystallization and...

Descripción completa

Detalles Bibliográficos
Autores principales: Luebbert, Christian, Stoyanov, Edmont
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10314205/
https://www.ncbi.nlm.nih.gov/pubmed/37396620
http://dx.doi.org/10.1016/j.ijpx.2023.100187