‘Radiation-induced pleomorphic sarcoma with rhabdomyoblastic differentiation of the lower limb following treatment of vaginal squamous cell carcinoma – A case report and review of the literature’

We present the case of a 59-year-old woman who developed a right thigh pleomorphic sarcoma with rhabdomyoblastic differentiation 6 years following radiotherapy for a vaginal squamous cell carcinoma. The overall 5-year survival for a gynaecological malignancy is more than 80 % and as overall cancer s...

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Detalles Bibliográficos
Autores principales: Nicholson, Anna, Jolley, Alexandra, Gowda, Raghu, Oehler, Martin K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10314220/
https://www.ncbi.nlm.nih.gov/pubmed/37396680
http://dx.doi.org/10.1016/j.gore.2023.101201
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author Nicholson, Anna
Jolley, Alexandra
Gowda, Raghu
Oehler, Martin K.
author_facet Nicholson, Anna
Jolley, Alexandra
Gowda, Raghu
Oehler, Martin K.
author_sort Nicholson, Anna
collection PubMed
description We present the case of a 59-year-old woman who developed a right thigh pleomorphic sarcoma with rhabdomyoblastic differentiation 6 years following radiotherapy for a vaginal squamous cell carcinoma. The overall 5-year survival for a gynaecological malignancy is more than 80 % and as overall cancer survivorship and life expectancy improves, the incidence of radiation-induced malignancy is increasing (Bjerkehagen et al., 2013). As the prognosis of those malignancies is usually poor, clinicians must have a high index of suspicion to try to detect these cases early.
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spelling pubmed-103142202023-07-02 ‘Radiation-induced pleomorphic sarcoma with rhabdomyoblastic differentiation of the lower limb following treatment of vaginal squamous cell carcinoma – A case report and review of the literature’ Nicholson, Anna Jolley, Alexandra Gowda, Raghu Oehler, Martin K. Gynecol Oncol Rep Case Report We present the case of a 59-year-old woman who developed a right thigh pleomorphic sarcoma with rhabdomyoblastic differentiation 6 years following radiotherapy for a vaginal squamous cell carcinoma. The overall 5-year survival for a gynaecological malignancy is more than 80 % and as overall cancer survivorship and life expectancy improves, the incidence of radiation-induced malignancy is increasing (Bjerkehagen et al., 2013). As the prognosis of those malignancies is usually poor, clinicians must have a high index of suspicion to try to detect these cases early. Elsevier 2023-05-30 /pmc/articles/PMC10314220/ /pubmed/37396680 http://dx.doi.org/10.1016/j.gore.2023.101201 Text en © 2023 The Author(s) https://creativecommons.org/licenses/by-nc-nd/4.0/This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).
spellingShingle Case Report
Nicholson, Anna
Jolley, Alexandra
Gowda, Raghu
Oehler, Martin K.
‘Radiation-induced pleomorphic sarcoma with rhabdomyoblastic differentiation of the lower limb following treatment of vaginal squamous cell carcinoma – A case report and review of the literature’
title ‘Radiation-induced pleomorphic sarcoma with rhabdomyoblastic differentiation of the lower limb following treatment of vaginal squamous cell carcinoma – A case report and review of the literature’
title_full ‘Radiation-induced pleomorphic sarcoma with rhabdomyoblastic differentiation of the lower limb following treatment of vaginal squamous cell carcinoma – A case report and review of the literature’
title_fullStr ‘Radiation-induced pleomorphic sarcoma with rhabdomyoblastic differentiation of the lower limb following treatment of vaginal squamous cell carcinoma – A case report and review of the literature’
title_full_unstemmed ‘Radiation-induced pleomorphic sarcoma with rhabdomyoblastic differentiation of the lower limb following treatment of vaginal squamous cell carcinoma – A case report and review of the literature’
title_short ‘Radiation-induced pleomorphic sarcoma with rhabdomyoblastic differentiation of the lower limb following treatment of vaginal squamous cell carcinoma – A case report and review of the literature’
title_sort ‘radiation-induced pleomorphic sarcoma with rhabdomyoblastic differentiation of the lower limb following treatment of vaginal squamous cell carcinoma – a case report and review of the literature’
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10314220/
https://www.ncbi.nlm.nih.gov/pubmed/37396680
http://dx.doi.org/10.1016/j.gore.2023.101201
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