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P110α inhibitor alpelisib exhibits a synergistic effect with pyrotinib and reverses pyrotinib resistant in HER2+ breast cancer

Human epidermal growth factor receptor 2 (HER2) plays a critical role in breast cancer progression in patients with HER2 overexpression, thereby driving the development of targeted drugs and advancing therapy strategies targeting this gene. Pyrotinib is a novel irreversible pan-ErbB kinase inhibitor...

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Detalles Bibliográficos
Autores principales:	Chen, Hao, Si, Yuhao, Wen, Jialiang, Hu, Chunlei, Xia, Erjie, Wang, Yinghao, Wang, Ouchen
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Neoplasia Press 2023
Materias:	Original Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10314290/ https://www.ncbi.nlm.nih.gov/pubmed/37348428 http://dx.doi.org/10.1016/j.neo.2023.100913

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