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Spinal Infection Due to Enterococcus faecalis as the First Manifestation of Colorectal Cancer

Spinal epidural abscess is a relatively infrequent surgical indication, but it may be neurologically compromising. The most frequent pathogen is Staphylococcus aureus, present in two-thirds of the cases. Enterococcus faecalis is part of the intestinal flora and is uncommon in this condition. Colorec...

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Autores principales: Manoku, Eni, Piedade, Guilherme S, Gelhardt, Andreas L, Cordeiro, Joacir G, Terzis, Jorge A
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cureus 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10314309/
https://www.ncbi.nlm.nih.gov/pubmed/37397680
http://dx.doi.org/10.7759/cureus.39815
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author Manoku, Eni
Piedade, Guilherme S
Gelhardt, Andreas L
Cordeiro, Joacir G
Terzis, Jorge A
author_facet Manoku, Eni
Piedade, Guilherme S
Gelhardt, Andreas L
Cordeiro, Joacir G
Terzis, Jorge A
author_sort Manoku, Eni
collection PubMed
description Spinal epidural abscess is a relatively infrequent surgical indication, but it may be neurologically compromising. The most frequent pathogen is Staphylococcus aureus, present in two-thirds of the cases. Enterococcus faecalis is part of the intestinal flora and is uncommon in this condition. Colorectal cancer is reported to be a cause of hematogenic translocation and distant infection. We present a case of an 82-year-old patient admitted for acute low back pain with increased inflammatory markers and negative blood cultures. An MRI revealed an epidural lumbar abscess with adjacent spondylitis. After surgical treatment, E. faecalis was identified, and antibiotics were adjusted accordingly. A colonoscopy revealed colon cancer. This is the first case in the literature of a spinal epidural abscess by E. faecalis as the first manifestation of a newly diagnosed colorectal cancer. When facing a spinal infection caused by atypical intestinal bacteria and no other clear sources, a colonoscopy should be considered.
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spelling pubmed-103143092023-07-02 Spinal Infection Due to Enterococcus faecalis as the First Manifestation of Colorectal Cancer Manoku, Eni Piedade, Guilherme S Gelhardt, Andreas L Cordeiro, Joacir G Terzis, Jorge A Cureus Gastroenterology Spinal epidural abscess is a relatively infrequent surgical indication, but it may be neurologically compromising. The most frequent pathogen is Staphylococcus aureus, present in two-thirds of the cases. Enterococcus faecalis is part of the intestinal flora and is uncommon in this condition. Colorectal cancer is reported to be a cause of hematogenic translocation and distant infection. We present a case of an 82-year-old patient admitted for acute low back pain with increased inflammatory markers and negative blood cultures. An MRI revealed an epidural lumbar abscess with adjacent spondylitis. After surgical treatment, E. faecalis was identified, and antibiotics were adjusted accordingly. A colonoscopy revealed colon cancer. This is the first case in the literature of a spinal epidural abscess by E. faecalis as the first manifestation of a newly diagnosed colorectal cancer. When facing a spinal infection caused by atypical intestinal bacteria and no other clear sources, a colonoscopy should be considered. Cureus 2023-06-01 /pmc/articles/PMC10314309/ /pubmed/37397680 http://dx.doi.org/10.7759/cureus.39815 Text en Copyright © 2023, Manoku et al. https://creativecommons.org/licenses/by/3.0/This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
spellingShingle Gastroenterology
Manoku, Eni
Piedade, Guilherme S
Gelhardt, Andreas L
Cordeiro, Joacir G
Terzis, Jorge A
Spinal Infection Due to Enterococcus faecalis as the First Manifestation of Colorectal Cancer
title Spinal Infection Due to Enterococcus faecalis as the First Manifestation of Colorectal Cancer
title_full Spinal Infection Due to Enterococcus faecalis as the First Manifestation of Colorectal Cancer
title_fullStr Spinal Infection Due to Enterococcus faecalis as the First Manifestation of Colorectal Cancer
title_full_unstemmed Spinal Infection Due to Enterococcus faecalis as the First Manifestation of Colorectal Cancer
title_short Spinal Infection Due to Enterococcus faecalis as the First Manifestation of Colorectal Cancer
title_sort spinal infection due to enterococcus faecalis as the first manifestation of colorectal cancer
topic Gastroenterology
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10314309/
https://www.ncbi.nlm.nih.gov/pubmed/37397680
http://dx.doi.org/10.7759/cureus.39815
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