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Gingival and alveolar mucosal reactive hyperplastic lesions: a retrospective clinical and histological study of 996 cases

BACKGROUND: gingival/alveolar mucosal reactive hyperplastic lesions (GRHL), including fibrous hyperplasia (FH), pyogenic granuloma (PG), peripheral ossifying fibroma (POF) and peripheral giant cell lesion (PGCL), are a common group of oral diseases. The aim of the present study was to access the fre...

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Autores principales: Baesso, Rafaela Carriço Porto, Azevedo, Rebeca Souza, Picciani, Bruna Lavinas Sayed, Pires, Fábio Ramoa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Medicina Oral S.L. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10314349/
https://www.ncbi.nlm.nih.gov/pubmed/36641745
http://dx.doi.org/10.4317/medoral.25766
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author Baesso, Rafaela Carriço Porto
Azevedo, Rebeca Souza
Picciani, Bruna Lavinas Sayed
Pires, Fábio Ramoa
author_facet Baesso, Rafaela Carriço Porto
Azevedo, Rebeca Souza
Picciani, Bruna Lavinas Sayed
Pires, Fábio Ramoa
author_sort Baesso, Rafaela Carriço Porto
collection PubMed
description BACKGROUND: gingival/alveolar mucosal reactive hyperplastic lesions (GRHL), including fibrous hyperplasia (FH), pyogenic granuloma (PG), peripheral ossifying fibroma (POF) and peripheral giant cell lesion (PGCL), are a common group of oral diseases. The aim of the present study was to access the frequency and distribution of the clinical and histological features of these disorders in a Brazilian population. MATERIAL AND METHODS: all specimens diagnosed as GRHL in three Oral Pathology laboratories were selected for the study. Clinical information was retrieved from the laboratory biopsy forms and hematoxylin and eosin stained histological slides were reviewed for analysis of the histological characteristics. RESULTS: final sample was composed of 996 specimens, including 463 FH (47%), 280 PG (28%), 183 POF (18%) and 70 PGCL (7%). Females were more affected by FH, PG, and POF, and most cases affected adults with mean ages ranging from 40 to 53 years. FH, PG, and POF were more common in the upper gingiva/alveolar mucosa. Most PG, POF and PGCL were pedunculated, in contrast with FH (p<0.001). PG, FH and POF were mostly red or normal mucosal in color, while PGCL were mostly red/purple (p<0.001). PGCL were larger, followed by POF, FH and PG (p<0.001). Some histological features were characteristically found in some conditions, but they were also encountered in other lesions with variable frequencies. CONCLUSIONS: Oral medicine specialists, oral pathologists and periodontists are usually the professionals in contact with patients presenting GRHL and it is of upmost relevance that they should be familiarized with their clinical and histological profile. Key words:Gingiva, lesions, reactive, hyperplastic.
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spelling pubmed-103143492023-07-02 Gingival and alveolar mucosal reactive hyperplastic lesions: a retrospective clinical and histological study of 996 cases Baesso, Rafaela Carriço Porto Azevedo, Rebeca Souza Picciani, Bruna Lavinas Sayed Pires, Fábio Ramoa Med Oral Patol Oral Cir Bucal Research BACKGROUND: gingival/alveolar mucosal reactive hyperplastic lesions (GRHL), including fibrous hyperplasia (FH), pyogenic granuloma (PG), peripheral ossifying fibroma (POF) and peripheral giant cell lesion (PGCL), are a common group of oral diseases. The aim of the present study was to access the frequency and distribution of the clinical and histological features of these disorders in a Brazilian population. MATERIAL AND METHODS: all specimens diagnosed as GRHL in three Oral Pathology laboratories were selected for the study. Clinical information was retrieved from the laboratory biopsy forms and hematoxylin and eosin stained histological slides were reviewed for analysis of the histological characteristics. RESULTS: final sample was composed of 996 specimens, including 463 FH (47%), 280 PG (28%), 183 POF (18%) and 70 PGCL (7%). Females were more affected by FH, PG, and POF, and most cases affected adults with mean ages ranging from 40 to 53 years. FH, PG, and POF were more common in the upper gingiva/alveolar mucosa. Most PG, POF and PGCL were pedunculated, in contrast with FH (p<0.001). PG, FH and POF were mostly red or normal mucosal in color, while PGCL were mostly red/purple (p<0.001). PGCL were larger, followed by POF, FH and PG (p<0.001). Some histological features were characteristically found in some conditions, but they were also encountered in other lesions with variable frequencies. CONCLUSIONS: Oral medicine specialists, oral pathologists and periodontists are usually the professionals in contact with patients presenting GRHL and it is of upmost relevance that they should be familiarized with their clinical and histological profile. Key words:Gingiva, lesions, reactive, hyperplastic. Medicina Oral S.L. 2023-07 2023-01-15 /pmc/articles/PMC10314349/ /pubmed/36641745 http://dx.doi.org/10.4317/medoral.25766 Text en Copyright: © 2023 Medicina Oral S.L. https://creativecommons.org/licenses/by/2.5/This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Research
Baesso, Rafaela Carriço Porto
Azevedo, Rebeca Souza
Picciani, Bruna Lavinas Sayed
Pires, Fábio Ramoa
Gingival and alveolar mucosal reactive hyperplastic lesions: a retrospective clinical and histological study of 996 cases
title Gingival and alveolar mucosal reactive hyperplastic lesions: a retrospective clinical and histological study of 996 cases
title_full Gingival and alveolar mucosal reactive hyperplastic lesions: a retrospective clinical and histological study of 996 cases
title_fullStr Gingival and alveolar mucosal reactive hyperplastic lesions: a retrospective clinical and histological study of 996 cases
title_full_unstemmed Gingival and alveolar mucosal reactive hyperplastic lesions: a retrospective clinical and histological study of 996 cases
title_short Gingival and alveolar mucosal reactive hyperplastic lesions: a retrospective clinical and histological study of 996 cases
title_sort gingival and alveolar mucosal reactive hyperplastic lesions: a retrospective clinical and histological study of 996 cases
topic Research
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10314349/
https://www.ncbi.nlm.nih.gov/pubmed/36641745
http://dx.doi.org/10.4317/medoral.25766
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