Fe(3+)-binding transferrin nanovesicles encapsulating sorafenib induce ferroptosis in hepatocellular carcinoma

BACKGROUND: Ferroptosis, iron-dependent cell death, is an established mechanism for cancer suppression, particularly in hepatocellular carcinoma (HCC). Sorafenib (SOR), a frontline drug for the treatment of HCC, induces ferroptosis by inhibiting the Solute Carrier family 7 member 11 (SLC7A11), with...

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Detalles Bibliográficos
Autores principales: Xiao, Youmei, Xu, Zhanxue, Cheng, Yuan, Huang, Rufan, Xie, Yuan, Tsai, Hsiang-i, Zha, Hualian, Xi, Lifang, Wang, Kai, Cheng, Xiaoli, Gao, Yanfeng, Zhang, Changhua, Cheng, Fang, Chen, Hongbo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10314404/
https://www.ncbi.nlm.nih.gov/pubmed/37391845
http://dx.doi.org/10.1186/s40824-023-00401-x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10314404/
https://www.ncbi.nlm.nih.gov/pubmed/37391845
http://dx.doi.org/10.1186/s40824-023-00401-x

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