Differential impact of BRAFV600E isoforms on tumorigenesis in a zebrafish model of melanoma

BRAFV600E comes as two main splicing variants. The well-studied ref isoform and the recently discovered X1 isoform are co-expressed in cancer cells and differ in terms of 3’UTR length and sequence, as well as C-term protein sequence. Here, we use a melanoma model in zebrafish to study the role playe...

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Detalles Bibliográficos
Autores principales: De Paolo, Raffaella, Sarti, Samanta, Bernardi, Sara, Cucco, Francesco, Tavosanis, Andrea, Pitto, Letizia, Poliseno, Laura
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Letter to the Editor
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10314448/
https://www.ncbi.nlm.nih.gov/pubmed/37393328
http://dx.doi.org/10.1186/s13578-023-01064-w

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10314448/
https://www.ncbi.nlm.nih.gov/pubmed/37393328
http://dx.doi.org/10.1186/s13578-023-01064-w

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