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TRPA1 activation and Hsp90 inhibition synergistically downregulate macrophage activation and inflammatory responses in vitro

BACKGROUND: Transient receptor potential ankyrin 1 (TRPA1) channels are known to be actively involved in various pathophysiological conditions, including neuronal inflammation, neuropathic pain, and various immunological responses. Heat shock protein 90 (Hsp90), a cytoplasmic molecular chaperone, is...

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Detalles Bibliográficos
Autores principales:	Radhakrishnan, Anukrishna, Mukherjee, Tathagata, Mahish, Chandan, Kumar, P Sanjai, Goswami, Chandan, Chattopadhyay, Subhasis
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2023
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10314470/ https://www.ncbi.nlm.nih.gov/pubmed/37391696 http://dx.doi.org/10.1186/s12865-023-00549-0

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