Cases of Yolk sac tumor associated with gynecological malignant tumor

BACKGROUND: Yolk sac tumour (YST) is the second most common ovarian germ cell tumour and usually presents in children and young women. However, tumours rarely occur as malignant gynaecological tumours with YST components. CASE PRESENTATION: We present one case of endometrioid carcinoma and clear cel...

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Autores principales: Wang, Shengchao, Chen, Kelie, Chen, Qin, Huang, Shuai, Lu, Weiguo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10314516/
https://www.ncbi.nlm.nih.gov/pubmed/37391759
http://dx.doi.org/10.1186/s12905-023-02495-w
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author Wang, Shengchao
Chen, Kelie
Chen, Qin
Huang, Shuai
Lu, Weiguo
author_facet Wang, Shengchao
Chen, Kelie
Chen, Qin
Huang, Shuai
Lu, Weiguo
author_sort Wang, Shengchao
collection PubMed
description BACKGROUND: Yolk sac tumour (YST) is the second most common ovarian germ cell tumour and usually presents in children and young women. However, tumours rarely occur as malignant gynaecological tumours with YST components. CASE PRESENTATION: We present one case of endometrioid carcinoma and clear cell carcinoma with YST components and two other cases of YSTs associated with high-grade serous carcinoma of the ovary in females. After surgery and adjuvant chemotherapy, the patient with endometrioid carcinoma had progressive disease and died 20 months later, and the other two were still alive at the last follow-up. CONCLUSIONS: To our knowledge, these mixed neoplasm associations are unusual, and these cases illustrate the diagnosis and prognosis of YST associated with malignant gynaecological tumours, emphasizing early recognition and aggressive treatment.
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spelling pubmed-103145162023-07-02 Cases of Yolk sac tumor associated with gynecological malignant tumor Wang, Shengchao Chen, Kelie Chen, Qin Huang, Shuai Lu, Weiguo BMC Womens Health Case Report BACKGROUND: Yolk sac tumour (YST) is the second most common ovarian germ cell tumour and usually presents in children and young women. However, tumours rarely occur as malignant gynaecological tumours with YST components. CASE PRESENTATION: We present one case of endometrioid carcinoma and clear cell carcinoma with YST components and two other cases of YSTs associated with high-grade serous carcinoma of the ovary in females. After surgery and adjuvant chemotherapy, the patient with endometrioid carcinoma had progressive disease and died 20 months later, and the other two were still alive at the last follow-up. CONCLUSIONS: To our knowledge, these mixed neoplasm associations are unusual, and these cases illustrate the diagnosis and prognosis of YST associated with malignant gynaecological tumours, emphasizing early recognition and aggressive treatment. BioMed Central 2023-06-30 /pmc/articles/PMC10314516/ /pubmed/37391759 http://dx.doi.org/10.1186/s12905-023-02495-w Text en © The Author(s) 2023 https://creativecommons.org/licenses/by/4.0/Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) . The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/ (https://creativecommons.org/publicdomain/zero/1.0/) ) applies to the data made available in this article, unless otherwise stated in a credit line to the data.
spellingShingle Case Report
Wang, Shengchao
Chen, Kelie
Chen, Qin
Huang, Shuai
Lu, Weiguo
Cases of Yolk sac tumor associated with gynecological malignant tumor
title Cases of Yolk sac tumor associated with gynecological malignant tumor
title_full Cases of Yolk sac tumor associated with gynecological malignant tumor
title_fullStr Cases of Yolk sac tumor associated with gynecological malignant tumor
title_full_unstemmed Cases of Yolk sac tumor associated with gynecological malignant tumor
title_short Cases of Yolk sac tumor associated with gynecological malignant tumor
title_sort cases of yolk sac tumor associated with gynecological malignant tumor
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10314516/
https://www.ncbi.nlm.nih.gov/pubmed/37391759
http://dx.doi.org/10.1186/s12905-023-02495-w
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