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Enhancement of TKI sensitivity in lung adenocarcinoma through m6A-dependent translational repression of Wnt signaling by circ-FBXW7

BACKGROUND: Tyrosine kinase inhibitors (TKIs) that specifically target mutational points in the EGFR gene have significantly reduced suffering and provided greater relief to patients with lung adenocarcinoma (LUAD). The third-generation EGFR-TKI, Osimertinib, has been successfully employed in clinic...

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Detalles Bibliográficos
Autores principales:	Li, Kai, Peng, Zi-Yang, Wang, Rui, Li, Xiang, Du, Ning, Liu, Da-Peng, Zhang, Jia, Zhang, Yun-Feng, Ma, Lei, Sun, Ye, Tang, Shou-Ching, Ren, Hong, Yang, Yi-Ping, Sun, Xin
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2023
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10314519/ https://www.ncbi.nlm.nih.gov/pubmed/37393311 http://dx.doi.org/10.1186/s12943-023-01811-0

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