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Method for estimation of apoptotic cell fraction of cytotherapy using in vivo fluorine-19 magnetic resonance: pilot study in a patient with head and neck carcinoma receiving tumor-infiltrating lymphocytes labeled with perfluorocarbon nanoemulsion
BACKGROUND: Adoptive transfer of T cells is a burgeoning cancer therapeutic approach. However, the fate of the cells, once transferred, is most often unknown. We describe the first clinical experience with a non-invasive biomarker to assay the apoptotic cell fraction (ACF) after cell therapy infusio...
Autores principales: | Ahrens, Eric T, Helfer, Brooke M, O’Hanlon, Charles F, Lister, Deanne R, Bykowski, Julie L, Messer, Karen, Leach, Benjamin I, Chen, Jiawen, Xu, Hongyan, Daniels, Gregory A, Cohen, Ezra E W |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BMJ Publishing Group
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10314637/ https://www.ncbi.nlm.nih.gov/pubmed/37339797 http://dx.doi.org/10.1136/jitc-2023-007015 |
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