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BiTE secretion by adoptively transferred stem-like T cells improves FRα+ ovarian cancer control

BACKGROUND: Cancer immunotherapies can produce complete therapeutic responses, however, outcomes in ovarian cancer (OC) are modest. While adoptive T-cell transfer (ACT) has been evaluated in OC, durable effects are rare. Poor therapeutic efficacy is likely multifactorial, stemming from limited antig...

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Detalles Bibliográficos
Autores principales:	McGray, A J Robert, Chiello, Jessie L, Tsuji, Takemasa, Long, Mark, Maraszek, Kathryn, Gaulin, Nicole, Rosario, Spencer R, Hess, Suzanne M, Abrams, Scott I, Kozbor, Danuta, Odunsi, Kunle, Zsiros, Emese
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BMJ Publishing Group 2023
Materias:	Immune Cell Therapies and Immune Cell Engineering
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10314690/ https://www.ncbi.nlm.nih.gov/pubmed/37647218 http://dx.doi.org/10.1136/jitc-2023-006863

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