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Predictive value of clinician impression for readmission and postdischarge mortality among neonates and young children in Dar es Salaam, Tanzania and Monrovia, Liberia

BACKGROUND: There are no validated clinical decision aids to identify neonates and young children at risk of hospital readmission or postdischarge mortality in sub-Saharan Africa, leaving the decision to discharge a child to a clinician’s impression. Our objective was to determine the precision of c...

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Autores principales: Rees, Chris A, Kisenge, Rodrick, Ideh, Readon C, Kamara, Julia, Coleman, Ye-Jeung, Samma, Abraham, Godfrey, Evance, Manji, Hussein K, Sudfeld, Christopher R, Westbrook, Adrianna L, Niescierenko, Michelle, Morris, Claudia R, Whitney, Cynthia G, Breiman, Robert F, Manji, Karim P, Duggan, Christopher P
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Publishing Group 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10314694/
https://www.ncbi.nlm.nih.gov/pubmed/37385735
http://dx.doi.org/10.1136/bmjpo-2023-001972
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author Rees, Chris A
Kisenge, Rodrick
Ideh, Readon C
Kamara, Julia
Coleman, Ye-Jeung
Samma, Abraham
Godfrey, Evance
Manji, Hussein K
Sudfeld, Christopher R
Westbrook, Adrianna L
Niescierenko, Michelle
Morris, Claudia R
Whitney, Cynthia G
Breiman, Robert F
Manji, Karim P
Duggan, Christopher P
author_facet Rees, Chris A
Kisenge, Rodrick
Ideh, Readon C
Kamara, Julia
Coleman, Ye-Jeung
Samma, Abraham
Godfrey, Evance
Manji, Hussein K
Sudfeld, Christopher R
Westbrook, Adrianna L
Niescierenko, Michelle
Morris, Claudia R
Whitney, Cynthia G
Breiman, Robert F
Manji, Karim P
Duggan, Christopher P
author_sort Rees, Chris A
collection PubMed
description BACKGROUND: There are no validated clinical decision aids to identify neonates and young children at risk of hospital readmission or postdischarge mortality in sub-Saharan Africa, leaving the decision to discharge a child to a clinician’s impression. Our objective was to determine the precision of clinician impression to identify neonates and young children at risk for readmission and postdischarge mortality. METHODS: We conducted a survey study nested in a prospective observational cohort of neonates and children aged 1–59 months followed 60 days after hospital discharge from Muhimbili National Hospital in Dar es Salaam, Tanzania or John F. Kennedy Medical Center in Monrovia, Liberia. Clinicians who discharged each enrolled patient were surveyed to determine their perceived probability of the patient’s risk of 60-day hospital readmission or postdischarge mortality. We calculated the area under the precision-recall curve (AUPRC) to determine the precision of clinician impression for both outcomes. RESULTS: Of 4247 discharged patients, 3896 (91.7%) had available clinician surveys and 3847 (98.7%) had 60-day outcomes available: 187 (4.8%) were readmitted and 120 (3.1%) died within 60 days of hospital discharge. Clinician impression had poor precision in identifying neonates and young children at risk of hospital readmission (AUPRC: 0.06, 95% CI: 0.04 to 0.08) and postdischarge mortality (AUPRC: 0.05, 95% CI: 0.03 to 0.08). Patients for whom clinicians attributed inability to pay for future medical treatment as the reason for risk for unplanned hospital readmission had 4.76 times the odds hospital readmission (95% CI: 1.31 to 17.25, p=0.02). CONCLUSIONS: Given the poor precision of clinician impression alone to identify neonates and young children at risk of hospital readmission and postdischarge mortality, validated clinical decision aids are needed to aid in the identification of young children at risk for these outcomes.
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spelling pubmed-103146942023-07-02 Predictive value of clinician impression for readmission and postdischarge mortality among neonates and young children in Dar es Salaam, Tanzania and Monrovia, Liberia Rees, Chris A Kisenge, Rodrick Ideh, Readon C Kamara, Julia Coleman, Ye-Jeung Samma, Abraham Godfrey, Evance Manji, Hussein K Sudfeld, Christopher R Westbrook, Adrianna L Niescierenko, Michelle Morris, Claudia R Whitney, Cynthia G Breiman, Robert F Manji, Karim P Duggan, Christopher P BMJ Paediatr Open Health Service BACKGROUND: There are no validated clinical decision aids to identify neonates and young children at risk of hospital readmission or postdischarge mortality in sub-Saharan Africa, leaving the decision to discharge a child to a clinician’s impression. Our objective was to determine the precision of clinician impression to identify neonates and young children at risk for readmission and postdischarge mortality. METHODS: We conducted a survey study nested in a prospective observational cohort of neonates and children aged 1–59 months followed 60 days after hospital discharge from Muhimbili National Hospital in Dar es Salaam, Tanzania or John F. Kennedy Medical Center in Monrovia, Liberia. Clinicians who discharged each enrolled patient were surveyed to determine their perceived probability of the patient’s risk of 60-day hospital readmission or postdischarge mortality. We calculated the area under the precision-recall curve (AUPRC) to determine the precision of clinician impression for both outcomes. RESULTS: Of 4247 discharged patients, 3896 (91.7%) had available clinician surveys and 3847 (98.7%) had 60-day outcomes available: 187 (4.8%) were readmitted and 120 (3.1%) died within 60 days of hospital discharge. Clinician impression had poor precision in identifying neonates and young children at risk of hospital readmission (AUPRC: 0.06, 95% CI: 0.04 to 0.08) and postdischarge mortality (AUPRC: 0.05, 95% CI: 0.03 to 0.08). Patients for whom clinicians attributed inability to pay for future medical treatment as the reason for risk for unplanned hospital readmission had 4.76 times the odds hospital readmission (95% CI: 1.31 to 17.25, p=0.02). CONCLUSIONS: Given the poor precision of clinician impression alone to identify neonates and young children at risk of hospital readmission and postdischarge mortality, validated clinical decision aids are needed to aid in the identification of young children at risk for these outcomes. BMJ Publishing Group 2023-06-29 /pmc/articles/PMC10314694/ /pubmed/37385735 http://dx.doi.org/10.1136/bmjpo-2023-001972 Text en © Author(s) (or their employer(s)) 2023. Re-use permitted under CC BY-NC. No commercial re-use. See rights and permissions. Published by BMJ. https://creativecommons.org/licenses/by-nc/4.0/This is an open access article distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited, appropriate credit is given, any changes made indicated, and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/ (https://creativecommons.org/licenses/by-nc/4.0/) .
spellingShingle Health Service
Rees, Chris A
Kisenge, Rodrick
Ideh, Readon C
Kamara, Julia
Coleman, Ye-Jeung
Samma, Abraham
Godfrey, Evance
Manji, Hussein K
Sudfeld, Christopher R
Westbrook, Adrianna L
Niescierenko, Michelle
Morris, Claudia R
Whitney, Cynthia G
Breiman, Robert F
Manji, Karim P
Duggan, Christopher P
Predictive value of clinician impression for readmission and postdischarge mortality among neonates and young children in Dar es Salaam, Tanzania and Monrovia, Liberia
title Predictive value of clinician impression for readmission and postdischarge mortality among neonates and young children in Dar es Salaam, Tanzania and Monrovia, Liberia
title_full Predictive value of clinician impression for readmission and postdischarge mortality among neonates and young children in Dar es Salaam, Tanzania and Monrovia, Liberia
title_fullStr Predictive value of clinician impression for readmission and postdischarge mortality among neonates and young children in Dar es Salaam, Tanzania and Monrovia, Liberia
title_full_unstemmed Predictive value of clinician impression for readmission and postdischarge mortality among neonates and young children in Dar es Salaam, Tanzania and Monrovia, Liberia
title_short Predictive value of clinician impression for readmission and postdischarge mortality among neonates and young children in Dar es Salaam, Tanzania and Monrovia, Liberia
title_sort predictive value of clinician impression for readmission and postdischarge mortality among neonates and young children in dar es salaam, tanzania and monrovia, liberia
topic Health Service
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10314694/
https://www.ncbi.nlm.nih.gov/pubmed/37385735
http://dx.doi.org/10.1136/bmjpo-2023-001972
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