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Lynch syndrome-associated chordoma with high tumor mutational burden and significant response to immune checkpoint inhibitors
Chordoma is a rare malignant bone tumor arising from notochordal tissue. Conventional treatments, such as radical resection and high-dose irradiation, frequently fail to control the tumor, resulting in recurrence and re-growth. In this study, genetic analysis of the tumor in a 72-year-old male patie...
| Autores principales: | , , , , , , , , , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Springer Nature Singapore
2023
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10314830/ https://www.ncbi.nlm.nih.gov/pubmed/37086325 http://dx.doi.org/10.1007/s10014-023-00461-w |