IDO1 is highly expressed in macrophages of patients in advanced tumour stages of oral squamous cell carcinoma

PURPOSE: Strategies for Indolamine-2,3-dioxygenase 1 (IDO1) inhibition in cancer immunotherapy once produced encouraging results, but failed in clinical trials. Recent evidence indicates that immune cells in the tumour microenvironment, especially macrophages, contribute to immune dysregulation and...

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Detalles Bibliográficos
Autores principales: Struckmeier, Ann-Kristin, Radermacher, Anne, Fehrenz, Michael, Bellin, Tamara, Alansary, Dalia, Wartenberg, Philipp, Boehm, Ulrich, Wagner, Mathias, Scheller, Anja, Hess, Jochen, Moratin, Julius, Freudlsperger, Christian, Hoffmann, Jürgen, Thurner, Lorenz, Roemer, Klaus, Freier, Kolja, Horn, Dominik
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2022
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10314853/
https://www.ncbi.nlm.nih.gov/pubmed/35963900
http://dx.doi.org/10.1007/s00432-022-04277-7

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