ASH1L-MRG15 methyltransferase deposits H3K4me3 and FACT for damage verification in nucleotide excision repair

To recognize DNA adducts, nucleotide excision repair (NER) deploys the XPC sensor, which detects damage-induced helical distortions, followed by engagement of TFIIH for lesion verification. Accessory players ensure that this factor handover takes place in chromatin where DNA is tightly wrapped aroun...

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Detalles Bibliográficos
Autores principales: Maritz, Corina, Khaleghi, Reihaneh, Yancoskie, Michelle N., Diethelm, Sarah, Brülisauer, Sonja, Ferreira, Natalia Santos, Jiang, Yang, Sturla, Shana J., Naegeli, Hanspeter
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10314917/
https://www.ncbi.nlm.nih.gov/pubmed/37393406
http://dx.doi.org/10.1038/s41467-023-39635-7

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