SUMOylation of Rho-associated protein kinase 2 induces goblet cell metaplasia in allergic airways

Allergic asthma is characterized by goblet cell metaplasia and subsequent mucus hypersecretion that contribute to the morbidity and mortality of this disease. Here, we explore the potential role and underlying mechanism of protein SUMOylation-mediated goblet cell metaplasia. The components of SUMOyl...

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Detalles Bibliográficos
Autores principales: Tan, Dan, Lu, Meiping, Cai, Yuqing, Qi, Weibo, Wu, Fugen, Bao, Hangyang, Qv, Meiyu, He, Qiangqiang, Xu, Yana, Wang, Xiangzhi, Shen, Tingyu, Luo, Jiahao, He, Yangxun, Wu, Junsong, Tang, Lanfang, Barkat, Muhammad Qasim, Xu, Chengyun, Wu, Ximei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10314948/
https://www.ncbi.nlm.nih.gov/pubmed/37393345
http://dx.doi.org/10.1038/s41467-023-39600-4

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