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Unusual presentation of Pott disease and diagnostic challenges in a resource-limited setting: a case report

BACKGROUND: Pott disease is rare and responsible for only 1%–2% of all tuberculosis cases. It poses diagnostic challenges in resource-limited settings due to unusual presentation and limited investigative capacity, resulting in debilitating sequelae if diagnosed late. CASE PRESENTATION: We present a...

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Autores principales: Byamukama, Anacret, Acan, Moses, Sebikali, Mugisha Julius
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10315039/
https://www.ncbi.nlm.nih.gov/pubmed/37393276
http://dx.doi.org/10.1186/s13256-023-04015-8
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author Byamukama, Anacret
Acan, Moses
Sebikali, Mugisha Julius
author_facet Byamukama, Anacret
Acan, Moses
Sebikali, Mugisha Julius
author_sort Byamukama, Anacret
collection PubMed
description BACKGROUND: Pott disease is rare and responsible for only 1%–2% of all tuberculosis cases. It poses diagnostic challenges in resource-limited settings due to unusual presentation and limited investigative capacity, resulting in debilitating sequelae if diagnosed late. CASE PRESENTATION: We present a case of severe Pott disease of the lumbar spine, with a large paravertebral abscess tracking down to the gluteal region in a 27-year-old Black African Ugandan woman living with human immunodeficiency virus, whose main complaint was right lower abdominal pain. She was initially misdiagnosed from the peripheral clinics as a case of lumbago and later with a psoas abscess. The diagnosis of severe Pott disease was established at the regional referral hospital following an abdominal computed tomography scan, and the patient was appropriately initiated on anti-tuberculosis drugs. However, only abscess drainage and provision of a lumbar corset were possible, with no neurosurgical intervention done on the spine due to financial constraints. Clinical review at 2, 6, and 12 months revealed improvement. CONCLUSIONS: Pott disease may present with non-specific symptoms such as abdominal pain resulting from pressure effects of an expansile cold abscess. This, coupled with limited diagnostic capacity in resource-limited settings; results in significant morbidity and possible mortality. Hence, there is need to train clinicians to increase their index of suspicion and equip health units with basic radiological equipment, such as x-ray, for timely detection and subsequent management of Pott disease.
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spelling pubmed-103150392023-07-03 Unusual presentation of Pott disease and diagnostic challenges in a resource-limited setting: a case report Byamukama, Anacret Acan, Moses Sebikali, Mugisha Julius J Med Case Rep Case Report BACKGROUND: Pott disease is rare and responsible for only 1%–2% of all tuberculosis cases. It poses diagnostic challenges in resource-limited settings due to unusual presentation and limited investigative capacity, resulting in debilitating sequelae if diagnosed late. CASE PRESENTATION: We present a case of severe Pott disease of the lumbar spine, with a large paravertebral abscess tracking down to the gluteal region in a 27-year-old Black African Ugandan woman living with human immunodeficiency virus, whose main complaint was right lower abdominal pain. She was initially misdiagnosed from the peripheral clinics as a case of lumbago and later with a psoas abscess. The diagnosis of severe Pott disease was established at the regional referral hospital following an abdominal computed tomography scan, and the patient was appropriately initiated on anti-tuberculosis drugs. However, only abscess drainage and provision of a lumbar corset were possible, with no neurosurgical intervention done on the spine due to financial constraints. Clinical review at 2, 6, and 12 months revealed improvement. CONCLUSIONS: Pott disease may present with non-specific symptoms such as abdominal pain resulting from pressure effects of an expansile cold abscess. This, coupled with limited diagnostic capacity in resource-limited settings; results in significant morbidity and possible mortality. Hence, there is need to train clinicians to increase their index of suspicion and equip health units with basic radiological equipment, such as x-ray, for timely detection and subsequent management of Pott disease. BioMed Central 2023-07-02 /pmc/articles/PMC10315039/ /pubmed/37393276 http://dx.doi.org/10.1186/s13256-023-04015-8 Text en © The Author(s) 2023 https://creativecommons.org/licenses/by/4.0/Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) . The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/ (https://creativecommons.org/publicdomain/zero/1.0/) ) applies to the data made available in this article, unless otherwise stated in a credit line to the data.
spellingShingle Case Report
Byamukama, Anacret
Acan, Moses
Sebikali, Mugisha Julius
Unusual presentation of Pott disease and diagnostic challenges in a resource-limited setting: a case report
title Unusual presentation of Pott disease and diagnostic challenges in a resource-limited setting: a case report
title_full Unusual presentation of Pott disease and diagnostic challenges in a resource-limited setting: a case report
title_fullStr Unusual presentation of Pott disease and diagnostic challenges in a resource-limited setting: a case report
title_full_unstemmed Unusual presentation of Pott disease and diagnostic challenges in a resource-limited setting: a case report
title_short Unusual presentation of Pott disease and diagnostic challenges in a resource-limited setting: a case report
title_sort unusual presentation of pott disease and diagnostic challenges in a resource-limited setting: a case report
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10315039/
https://www.ncbi.nlm.nih.gov/pubmed/37393276
http://dx.doi.org/10.1186/s13256-023-04015-8
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