Extracellular matrix remodelling and stiffening contributes to tumorigenesis of salivary carcinoma ex pleomorphic adenoma——A study based on patient-derived organoids

BACKGROUND: Salivary carcinoma ex pleomorphic adenoma (CXPA) is defined as a carcinoma that develops from benign pleomorphic adenoma (PA). Abnormally activated Androgen signaling pathway and amplification of HER-2/neu(ERBB-2) gene are known to be involved in CXPA tumorigenesis. Recent progress in tu...

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Detalles Bibliográficos
Autores principales: Chen, Wanling, Gu, Ting, Chen, Qianqian, Qu, Chuxiang, Zhang, Chunye, Hu, Yuhua, Xia, Ronghui, Zhang, Ying, Wang, Min, Huang, Xinyi, Li, Jiang, Shi, Chaoji, Tian, Zhen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10315042/
https://www.ncbi.nlm.nih.gov/pubmed/37393249
http://dx.doi.org/10.1186/s13578-023-01071-x

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